Busch Lab

ZMP

jag1a

Ensembl ID:
ENSDARG00000030289
ZFIN ID:
ZDB-GENE-011128-2
Description:
Protein jagged-1a [Source:UniProtKB/Swiss-Prot;Acc:Q90Y57]
Human Orthologue:
JAG1
Human Description:
jagged 1 [Source:HGNC Symbol;Acc:6188]
Mouse Orthologue:
Jag1
Mouse Description:
jagged 1 Gene [Source:MGI Symbol;Acc:MGI:1095416]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa45084 Nonsense Mutation detected in F1 DNA Not yet available
sa168 Nonsense Available for shipment Available now
sa11248 Nonsense Available for shipment Available now
sa1989 Essential Splice Site F2 line generated Not yet available
sa39691 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa45084
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047851 Nonsense 211 1242 4 27
ENSDART00000123632 Nonsense 211 1242 4 28
ENSDART00000137172 Nonsense 211 1253 4 26
Genomic Location (Zv9):
Chromosome 1 (position 51651276)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 50497773
GRCz11 1 51141572
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTGGCTGTAATAAGTTCTGTCGGCCCAGAGACGACTTTTTCGGCCACTA[T/A]ACCTGCGATCACAACGGAAACAAGACCTGTTTGGAAGGATGGGCCGGCCC
Long Flanking Sequence:
GTGAAGTTCATGTGATGCTCATGTAGTTTTTCCTGTAAGGGACATGAAGTATAAATCATAGAAGGAAACCTTTGTGATATTTCTAATCTGTTGTGTGTGTTATCCTAAAATCATCCCATTTGCAGTATAGAACAGACATTTAGCCTAAAGTCTACTTTTGTTGTTCAGAAACATCTCAACCATAAATCCAGTGCCTAAATCTGCATGTTTTGAGAGTTAGTGGTGTTCGTAATTTCATATTTAAGCTAAACAGAAGTGTCATTAAACCACAGCTGTGATCTATAATGTAATGCTCTCTTCTTTATAGGCATAAATGGACAAGTGATCGAGAAAGCGGTGCAGTCGGGCATGATCAACCCAAACCGTCAATGGCAGGTCCTGAAGCACAACGGCCCCGTGGCTCAGTTCCAGTACCAAATTCGGGTGACCTGCGACGAGCACTACTTTGGCTTTGGCTGTAATAAGTTCTGTCGGCCCAGAGACGACTTTTTCGGCCACTA[T/A]ACCTGCGATCACAACGGAAACAAGACCTGTTTGGAAGGATGGGCCGGCCCAGAATGCAACACTGGTGAGGGGACGGGGCTGTTTATCAGATTTATAATGCTGTTCCAATGCTAGAGCATGTTGTTTTCATATGTGAGGGCTCCCACTAAGTAGATATGCATTTAAAAGACATCTTATAGACATCCAAATCTAGATGTCTTGGCTTTGTTTGGGCTGACAATCTAATAATAGTCTAGTAATCTAACACAGATCAGACAGGCTGCACATGTGTCTTTGATATCTGTTTAATGACTAGTCAAATTTAGGCTTGTTTTAGCCATGACATCTATGTTCGGATGTCTGTATTTTAGATGTTTAGCTGTAAGCTGTTAGTTCAGGTCTGTAAGTCACAAAACACTGGAAAACTAATAGATAGATATTCATTGGTCTAAAGCATGGGAATGGGGTTATTCAGGCTTGTTTAGACTAAACTTATTAATGCTCTGTAGATGTAGATGACC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa168
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047851 Nonsense 438 1242 10 27
ENSDART00000123632 Nonsense 438 1242 10 28
ENSDART00000137172 Nonsense 438 1253 10 26
Genomic Location (Zv9):
Chromosome 1 (position 51640321)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 50486818
GRCz11 1 51130617
KASP Assay ID:
554-0096.1 (used for ordering genotyping assays)
KASP Sequence:
CGTGCGTCAATGCCCACTCCTGCCGCAATCTGATTGGTGGATACTTCTGC[G/T]AGTGCCTGCCTGGCTGGACGGGACAGAATTGCGACATCAGTAAGTATTTC
Long Flanking Sequence:
TCCAGTTTCTCCCACAGTCCAAAGACATGTGCTTGGTGAATTGAATAAACTAAATTGGCTATAGTGTATGAGTGTGTATGTGAGTTTCCCAGTACTTGGTTGTGGCTGAAAGGGCATCCGCAGTGTAAAACATGCCAGTATAGTTGGCGCTTCATTCTGTTTTGGGGACCCTAGATAAATAAGGGATTAAGCTGAAGGAAAATAAATAAATGGGGTGCCAATATTTATGCACACACATGTTCTTTCCAATAAAACAGTTGTGTTTGCAATTATTTGTTCTAAATTAGCTTTTTTGTTAATATTCTGAGCAAAAGATCAACATTTCACACACATCTTAGTGGAGGTAACTGCATATAGTTCTGTTTGGCTGCGTGTGTGTTTGGACTGCGCTCACACTAGTTTCTCTTTTTTCCATTTTTGGCCCAGATGCTAATGAGTGTGAGGAAAGCCCGTGCGTCAATGCCCACTCCTGCCGCAATCTGATTGGTGGATACTTCTGC[G/T]AGTGCCTGCCTGGCTGGACGGGACAGAATTGCGACATCAGTAAGTATTTCACAGTGTCAGATTAAAGCAACGTGAGATTGACTACATAGGCGCTCTGAGAGATCTGCAAGTGAGTTTAACTACAGGTCGGTACTGATAGCTTGCTGAAGGAAAATGCAGCAGAAAAAACAAAACAAAATTTGAATATGAGTACTTCATGAAAATGTATAAAGCTTCATATATTAGGGTTTATTTAATAATTGGTCTGATTTTATTATCATTTTATTTCAGCTTTTGTTTAAAGAGGACCTATTATGCAAAAATCACTTTTATAAGGGGTTTAAACGCAGTTGTGTGGCAACAGTCTGTGAATATAACCAGTGTCTAAGGGTAAAAATGTATTAATTGTATTAATATATTAATCTGTTTATAACAGCGGTGTTAAACGTACGGCCCGCAGGCCGGATCAGGCCCACAAACGAATTAATGCAGCCCGCGAGATGATTCTGTGAGCTGCAATT
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461

Mutation Details

Allele Name:
sa11248
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047851 Nonsense 618 1242 14 27
ENSDART00000123632 Nonsense 618 1242 14 28
ENSDART00000137172 Nonsense 618 1253 14 26
Genomic Location (Zv9):
Chromosome 1 (position 51631075)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 50477572
GRCz11 1 51121371
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CCACACGGCCGCTGCCKTAGCCACAGCCAYGCCGGAGGACACTTCAGCTG[C/A]GACTGTCAAGACGGCTTCACCGGGACCTACTGCCACGAGAGTAAGTGAAT
Long Flanking Sequence:
AAGAAAATATTACTAAATATTCTAATAAATATTCATATCGACATTATAATTATTTTCATTATTGCAATAATAATTATTATGCTGTAAATTTAAAAAAATATATGAGGTATTATTGAATATTATAATAAATATTAATAATTGCTAATTAATAATTTGCAAGTAATTTAAACAAAAATAGTTTATTTTCATGAAAACTGTATAAAGAGTCAAGCTAAAATTAGTTTGGTTTCTAGATCTAGATTGATAGTCCATGTTTGTCAAACTAAATTTAAGACTACATAGATTATCAGCAACCATCTCAACTTTAAGAAGACACACACTTTGACCATCCGCTCTCATTAAACCCTGTGCTCTTTGTTGTGTCCTGCAGTGATTGACAGCTGTACGGTGGCGGTGGTGTCAAACAGCACCCCAGGCGGTCTGAGGCTAATCTCTTCCAGTGTGTGCGGTCCACACGGCCGCTGCCGTAGCCACAGCCATGCCGGAGGACACTTCAGCTG[C/A]GACTGTCAAGACGGCTTCACCGGGACCTACTGCCACGAGAGTAAGTGAATATAAGACAGCCAGAGTTCACATCCATTTACAGGTGTTTATTGAAAGAGTTCAGCAAATCCAAATCATAAATTCATTTATCAGGGGTCACCACAGTGGAATGAACCGCCAACTATTCCACCATATGTTTTACACAGCAGATGCCCTTCCAGCCGCAGCCCAGTACTTGGAAACACCCATACACTCTCACAATCACAGACACACTTATACATTACGGCCAATTTAGTTGACCAAATTCACCTATAGCGCATGCAAACTCACACACAGAACTGCCAACTGACCCGAGACTCGAACCAGCGACCTTCTTGCTGCAAGGTGACAGTGAGCCCATCTGTCGCCCCAAAACATAAATCAAAGTTGAAAGAAGGGGAATGGATAAACACTGGTCTGCTTTTCAAACACTGCTTCATGAAGCTTTACGAATCTTTTGTTTTGAATCAGCAGTTTCAGAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa1989
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047851 Essential Splice Site 823 1242 20 27
ENSDART00000123632 Essential Splice Site 823 1242 20 28
ENSDART00000137172 Essential Splice Site 823 1253 20 26
Genomic Location (Zv9):
Chromosome 1 (position 51623395)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 50469892
GRCz11 1 51113691
KASP Assay ID:
554-2934.1 (used for ordering genotyping assays)
KASP Sequence:
TACCGCTGTGAGTGCGCCAGTGGCTTYGCAGGACCAGACTGCCGCATCAG[T/C]GAGTGAATGCTTTATTCAGCATTTAGYAGTACGATTTTATTATAAAGAGT
Long Flanking Sequence:
TTAATTTAATTTATAAACACCAGAAACAATGTTTAATCTTCACTTTCATCTTCACTAAACCACTTACATGTATTAAATATTATTAATGTACGGTAAGCGATTAATTGTATTTTATTAATGACATTTAATTTGATTTTATAGCCATACACTGTGATAAACTGCAGTATTTATCTTCATGATGAATTATGATACATTTTAGCTGAAAAAATTACAAGTTTTGCCTGAAAATACCACAAATGTAGCTTTTTAATGGAGGAGCTTTGGCTGCATACAGCATCAATTGAATGTATTAAATATTTTTTATTGAAACCTGTTAAATTAACATTTTTTGTAACAATGAACACATTTGTGAACATTTTGAAAATCTCCCATCATTTTCCAAGTCATCTTATCAATATGTGTTCTCTGTGCAGTTATAACAGTGGGACATGTGTGGATGGGGATAACTGGTACCGCTGTGAGTGCGCCAGTGGCTTTGCAGGACCAGACTGCCGCATCAG[T/C]GAGTGAATGCTTTATTCAGCATTTAGTAGTACGATTTTATTATAAAGAGTGATTGCACGTTAAAACGGTTCTCTTTCCCTCTACAGACATCAATGAGTGCCAGTCGTCACCCTGTGCGTTCGGCTCTACCTGTGTGGATGAAATTAATGGCTACCGCTGCTTGTGTCCACCAGGCAGAACCGGACCCAGATGTCAGGAAGGTACAGTTCCCATTATTTATACTTGCACTTTAATCCAAATTAAAGGGAGACTTAAAAATTGTATTTAGTCACTATGTAATCTGTTTTATGGCTTTGCTTTTTCTGTTGGACACAAAAGAAATAATGTTGAAGCTCAAAACCATTGACTTCCATAGTAGGGAAAACAAACACTATAAAAGTCAATGGTTACAGGTTACAGCATTCTTCAAAATAACTTTTTTTGTATTCATCAGAAAAAATAACCAAGTAAAGTGTGAGTGAATGAATTTAATAGTATTTATCAAGCTTTTTATTGCTCAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa39691
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047851 Nonsense 1057 1242 26 27
ENSDART00000123632 Nonsense 1057 1242 26 28
ENSDART00000137172 Nonsense 1068 1253 25 26
Genomic Location (Zv9):
Chromosome 1 (position 51619715)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 50466212
GRCz11 1 51110011
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGAGCAAACACAGTGCTAACAGCTCCGTCATCGGCTCCATCGCTGAGGTT[C/T]GAGTGCAGCGCAAACAACCGCAAAACCCCAACGGTGAGACATCACAGCAA
Long Flanking Sequence:
CGCCAGTAACGAGATCCATGTGGCCATTGTGAGTGATTTAGCGCAAAATAACTCTAATAAACTTTTATTTGCAATTTTTTATGAAATGTCTTATTATCCATATGGTATTAAAGAATGACAAGAAATATCGAATTCATAATGGTGTATAATAATGTATTATATTATTATTGTTCTATTTTGTCATTTTTATGGAATTTATATAATTCAAATAAAATGAATACTATATAACACTATTATTCTTGATTATTTTATTTTTATTTGTTGTATTTGTGTTGTTAAATATTTACCGTAATGCATTTCATTTTGCTTTATTTAAATTAGAACATTTAAGTCATAAAAAAATGACTTGAATAAAAAAAAAAAAATGTTGTGTTTTCTAGCATGTGACTGAGAACGGCATTCATGGCCGGGTTCCTGTTAAGGAAATTACAGACAACATCATTGATCTGGTGAGCAAACACAGTGCTAACAGCTCCGTCATCGGCTCCATCGCTGAGGTT[C/T]GAGTGCAGCGCAAACAACCGCAAAACCCCAACGGTGAGACATCACAGCAAGCTCTTAAACTTTACAGGAAACAGTCTTGAAAGAACGTTTTACTGGGCAAGGATTGCATTAAATTTATCAAAAGTGACAGTAAATTCATGTTACAGAAATTGTATTTTAAATAAATGTTGTTCTTTTGAACAAAAAACATCATAATGACTGCTTAAGGACCATCTAGCTTTTCTCACAGGAATACACAGCATTTTTAAATATTATGCATGTTTTCAATATTATTTACGTAATAATAACACTTTTTGTCAACAATAAAAGAACATTAATAAATACAACCATTTAAATGAATTTAAAAATGTAAAAATAAATTAAATTTCACAGTATTACTGTTTTTAGTGTTAATGTATCGGCCAATAATCGGTATCAGCTTATTGCTAAAAATCAGCCAACTATAAGGTTAAATTATATTCTCAATCAAAATAAGGCAGGAAAAATGCTAATTTGTATAA
Associated Phenotype:
Not determined