ZMP
twf1b
Ensembl ID:
ZFIN ID:
Description:
twinfilin, actin-binding protein, homolog 1b [Source:RefSeq peptide;Acc:NP_001002304]
Human Orthologue:
TWF1
Human Description:
twinfilin, actin-binding protein, homolog 1 (Drosophila) [Source:HGNC Symbol;Acc:9620]
Mouse Orthologue:
Twf1
Mouse Description:
twinfilin, actin-binding protein, homolog 1 (Drosophila) Gene [Source:MGI Symbol;Acc:MGI:1100520]
Alleles
There are 2 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa11093 | Essential Splice Site | Available for shipment | Available now |
| sa14476 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa11093
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000015134 | Essential Splice Site | 294 | 349 | 8 | 9 |
| ENSDART00000129518 | Essential Splice Site | 320 | 375 | 8 | 9 |
The following transcripts of ENSDARG00000011661 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 4 (position 13261113)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 4 | 14197485 |
| GRCz11 | 4 | 14196334 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTCTCATAGACACTGTRRAGAGAAACTTGGGCATTGAAATTGYCAAAAAG[G/A]TATTGCATGTTACTTTAGTATAAAGTTCAGCATACGCCATGCTGTTTAAA
Long Flanking Sequence:
ACAGCTTTGTGAAATATCTAATTATTGTCATGGAATTATGTATTTAAATATATTCCCGATTTATCTAAATTGGAATTTGTATTAAATGTTGACAGAGAACAGCTTAAGCATAATAAATAATGGTACATTACATAAAATGAATTACTTACTAGGAACATCTAATGATTTCCCAGGGATGGGTTGCGGCTGGAAGGACATCCGCTGCGTAAAAACATGCTGGATAAGTTGGCTGTTCATTCCGCTGTGGCGACCCCGGATTAATAAAGGGACTAAGCCAAAAAGAAAATGAATGAATGAATGAATGAATGAATGAATGAATGAACATCTAATGATCGTCTCTGAACACAACCAATATGATTAATCTTTTTGTGTCTGCAGTGTTCATCTACTCTATGCCTGGTTATAAATGCAGCATCAAGGAGAGAATGCTGTATTCAAGCTGCAAGAACCCTCTCATAGACACTGTAGAGAGAAACTTGGGCATTGAAATTGCCAAAAAG[G/A]TATTGCATGTTACTTTAGTATAAAGTTCAGCATACGCCATGCTGTTTAAAGGGATGGTTCACTCAAAAAAATGTTTAAATGAGCAAAATTTTAGCAACTTCAGGCCATTAGAAATGTACTTTTATTCTTCAGGCGGACATGAAATAATAGTATTAGCTGAAACTATGGTGCTTGGTGATTTCATAAAATCAAGCCAATGGCTATCAGCACTTACAAACATATACAGGCAAAACTAAATTAAAACTTGTTGCTTTTGATAATACATTGAGATCTTCTGATGCGAAATGATTAATCTGTGAATATTACTAACTGTTATACTAACGCCTGTTTCACACCGCAAGCGTCAGCGGCGCGTGAGCAGAGCGTGAGCAGCGCGTATGTCGAGCAGTAGCAGCACGCAGGCGTTTGCCTTTCACACCAGCTGCGTCTGCAGCGCGCAGGTTTTCGGCAGCTGCTGCTGAGATCAACCTATCTCTGTCTATTCTATCTAGTTACCCCTC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa14476
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000015134 | Nonsense | 333 | 349 | 9 | 9 |
| ENSDART00000129518 | Nonsense | 359 | 375 | 9 | 9 |
The following transcripts of ENSDARG00000011661 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 4 (position 13259329)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 4 | 14195701 |
| GRCz11 | 4 | 14194550 |
KASP Assay ID:
2259-4702.1 (used for ordering genotyping assays)
KASP Sequence:
AACATGCGCACAAGCAAGCTTTTGCCAAACCCAAGGGGCCAACAGGGAAA[A/T]GAGGAGGCCGTCGAATCACACGGGCACCAGGGGACGGCGGCGACGATGAT
Long Flanking Sequence:
CAATGTGTTTTGGTCATTCTCAATGCACTGTCACTTTAATTGAGCTTGATCAGCGCGTCAAAAATAGACCCAGCGCCGAAACTATCGCTGCACTGCTGCTTCGGCGACGCTCACGCCTCGCTCTGACGCGCTGCTGCTGCGTGCGGTATGAAAGCTCTAATCTGTTAACATGGACGCCGAAAACACACGCACTGCTCACGCTCTGCTCACGCGCCGCTGACGCTTGCGGTGTGAAACAGGCGTTAGAAAAAGCTCTTGACTGACCTGAGAGTTTATAAATAACCAGCAAATTTTCATTTGGTGGTGAACTGCCCCTTTAATTCCTTGAGGCATGAACGTGCATTTAATGTTACAGCTTCTCATTTCGTGCTTCTTCACCTTTTCAGCTGGAAATCGACAACGGTGACGAACTAACCAGTGACTTTATGTACGAAGAGGTTCACCCCAAACAACATGCGCACAAGCAAGCTTTTGCCAAACCCAAGGGGCCAACAGGGAAA[A/T]GAGGAGGCCGTCGAATCACACGGGCACCAGGGGACGGCGGCGACGATGATTAAAACCCTCTTCCTATTCCACGACTGACACTTAGTCTAATGAATCCCGTCCTCAAGCCAATCCCATTTTTACCTTGACTCATGTAGACCACAGCGCTATAGACTGATCTATGCACAAAGTACAACACTAAGGCCTGTGAAATGACACTTTGTAGCTTGCAATATGAAACGCTAGGTTGAAGAAAACAGAAGTACACTAGAATGTATTTTAAGAAGCTCCTGGTAATAGTTTTACACTATTACGCTGTTTACCTGCATATTAGCCAATAGAGTGCAATACTGATGGAGATCCTCCATTTAGTGCTTATATTTTCCTTAAGAAAAACTTCAAAAATGAAATGCGTGTAATCTAGTACAGGTATAAACCGCACTTTCTGTGGTAGATTTACATTTTAGCATTAATATTTGTCTGGGAATTTGGTTTTAGTGTGATTTGTGCTTGGAAAACAT
Associated Phenotype:
Not determined