Busch Lab

ZMP

fgfr2

Ensembl ID:
ENSDARG00000058115
ZFIN IDs:
ZDB-GENE-030323-1, ZDB-GENE-030323-1, ZDB-GENE-030323-1, ZDB-GENE-030323-1
Description:
Fibroblast growth factor receptor 2 [Source:UniProtKB/Swiss-Prot;Acc:Q8JG38]
Human Orthologue:
FGFR2
Human Description:
fibroblast growth factor receptor 2 [Source:HGNC Symbol;Acc:3689]
Mouse Orthologue:
Fgfr2
Mouse Description:
fibroblast growth factor receptor 2 Gene [Source:MGI Symbol;Acc:MGI:95523]

Alleles

There are 8 alleles of this gene:

Allele Name Consequence Status Availability
sa30975 Nonsense Mutation detected in F1 DNA Not yet available
sa10729 Nonsense Available for shipment Available now
hu2987 Nonsense Available for shipment Available now
sa24945 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa42296 Nonsense Mutation detected in F1 DNA Not yet available
sa35586 Nonsense Mutation detected in F1 DNA Not yet available
sa42295 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa30975
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000007408 Nonsense 37 817 2 18
ENSDART00000080914 Nonsense 37 815 2 18
ENSDART00000080916 Nonsense 60 840 1 18
ENSDART00000098269 Nonsense 60 751 2 17
Genomic Location (Zv9):
Chromosome 13 (position 47032758)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 46285109
GRCz11 13 46421574
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTGTGGCACGGCCGTCATTGAAGATTGACTTGGTGAATACATCTGCACCT[G/T]AAGGTAAGACATTTGAGCGATGGAAGATGCTACTTTAAGAAATCACAACT
Long Flanking Sequence:
ATTTTAATAATTTAATCAGTTTTAACAATTTTTTAAGATACACAAAGTTTAACTTAATATTTTAAGTCAGTTTAATTCTATATTCTGTATTCTCTACAGTCATCAGTTGAGATGACAAAAACTAAAAAACTAAAAAAAAAATGTTTTTTTTTTTTTCTACATTGTATGCGTGGTTACAGTCTTTTCTAAGTGTCTAAACCTTCTCATTTTCTCCTGGGTGACCCCTTGATCTGTCATCCATCTTCAGCCCAGGTGATTGGTGGGAATTCCAGTGAGTGACCGACCGTACAGCCTGCAGTTGATGGTTGGGTGGAGCCCCTCAGATGGGATCCGTGTCCAGGGGGAGGCCGAGGAGGAGGGGGGGATGTGGAGACACGCCCACCACTGATGGGATGTTCGCCCGAGGGTGGCTTCTGGGTGCTCTCCTGCTAATGACCCTGGCAACGGTATCTGTGGCACGGCCGTCATTGAAGATTGACTTGGTGAATACATCTGCACCT[G/T]AAGGTAAGACATTTGAGCGATGGAAGATGCTACTTTAAGAAATCACAACTGCTGCTGCTTAAAGATGCTGTTTAGTTACTATGAAATCAAGCTGCACCTATAGTTGAAGTCAAAATTATTAGGCCTCCTGTGAATTTCTTTCAAATATTTTCTAAATGATGTTTAACTGAGCAAGGAATTTTTAAAAATATTTCCTATAATATTTTTTCTTCTGGAGAAAGTCTTATTTGTTTTATTTCGGCTAGAATGAAAGCGTTTTTTATTTAAAAAAAAAATCATTTTAAGGTCAATATTATTAGCCCCCTTAAGTTTTTTTTTTTTTTTTTTTGATTGTCTACATGACTAGCTTTTATGTCTCATCATCATCATCATCATCATCATAATTCTGACTTCAACTGTATGTGCATAAATTTTTGGTTGTTATTGGGGGAAGTAGGGTTGTCCAATATGATATTATGTATATTATAAACTGTGCAATATGATATATACTGCAATATATA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa10729
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000007408 Nonsense 421 817 9 18
ENSDART00000080914 Nonsense 419 815 9 18
ENSDART00000080916 Nonsense 444 840 8 18
ENSDART00000098269 Nonsense 355 751 8 17
Genomic Location (Zv9):
Chromosome 13 (position 46957498)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 46209849
GRCz11 13 46346314
KASP Assay ID:
2260-6940.1 (used for ordering genotyping assays)
KASP Sequence:
CTAAGAAGCCTGATTTCAGCAGTCAGCCAGCAGTGCACAAGCTCACCAAA[C/T]AGATCCCCCWGCGCCGCCAGGTAACAGAAAGTAGATAAAGAGTTCCAGAA
Long Flanking Sequence:
CAGTGCAAATTTAGATAGATTTAGTGTCTTTGAAAAACCCTCAGTGTGTGATGTGTGTGTGTGAGTGTGTGTGTGTGTGTCTCTTCCTCTCTCATTTCTTCCCATTCTTCCTACTGACCCAATATCCTTCCCAGATACCTTAATGTCCTTCATAAGCATCTTATAATATGCTTTACCAACATTAAAGTTTCTGGTTCGGTATTCTTCACCTGTATCATAATTTATTATTGGTCACACTTTATTTTAATATACAATTCACTCTGTTAACAAAGCATCAACTGAGACCTTTAGCACAGTCAAACACTTCTGAATATTGCTTCACAGCTGAGACGAATCCCATCGAGACGGATTATCCTCCAGATTATGTGGAGATCGCCATCTACTGTATAGGTGTGTTTCTGATCGCCTGTATGGTGGTGATCGTGGTGGTTTGCCGGATGAGGACGTCGGCTAAGAAGCCTGATTTCAGCAGTCAGCCAGCAGTGCACAAGCTCACCAAA[C/T]AGATCCCCCTGCGCCGCCAGGTAACAGAAAGTAGATAAAGAGTTCCAGAAACCTTATACACACTTACATTCACACTAATAATGACAATAAGCACGTTTACATGGACACCAATTCTCCGATTTTTATACGATTAGGACAATACTCTGATCAAAAGTCCACTATGTAAACAGCGATTTTTTTTTTTTATTACCTTATCCAACTAAACATAAATGGAGTTAAGACTTGGAGTATTCCTATTTTACTGGCATTATTGAAGTGCAGTACAGACATGTAAACACCACAATCAAACTATTGCCGCCGTGTAGGACTTTTAGGCGCATTTTTTGATAGGATATTCCATACACACACAGCTGTTTCACACAGCTGTTTGTTATGCCACAGCCATGTCACCCTGCAGCCCAAGACCGGTTACTCACTGAAGCTAAGCAGGGCTGAGCCTGGTCAGTACCTGAATGGGAGACCACTAGGGAACACTAGGTTGCTGTTGGAAGTGGTGTTAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
hu2987
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000007408 Nonsense 547 817 12 18
ENSDART00000080914 Nonsense 545 815 12 18
ENSDART00000080916 Nonsense 570 840 11 18
ENSDART00000098269 Nonsense 481 751 11 17
Genomic Location (Zv9):
Chromosome 13 (position 46933179)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 46185530
GRCz11 13 46321995
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GATGGAGATGATGAAGATGATTGGCCGGCACAAGAACATCATCAATCTGT[T/A]GGGAGCGTGCACACAGGATGGTGAGGGATTTATTTTCACTATAGAAAGCC
Long Flanking Sequence:
TAGTATGATCGAGTATTTTTGGAGTGTACAACAGCAGGCATGTCTAAACTCGGTCCTAGAGGGTCGGTGTCCTGCAAAGTTTAGTTCCAACCCCAGTCAGACACGCCTTGGCTAGCTAATCAAGCTCTTACTAGGTTTTCTAGAAACATCCTTGCAGTTGCCTAAGGCAAGTTAGAGCTAAAATCTGTAGGACACCAGCCCTCCAGGACCGAGTTTGGACACCCCTGATCTACAGTGTAAACCCAGAACAATGAGAAGAGTTGTATCCCATGATAAGACGAAGCTTGCAGCCAAGCATGCAGTTCCCTAGTACTACTTTACAATGTCATATGATCTCAGCTGAGCAGGAAATAGGAAGAATGGCTTTTTCTGAATGAGGTTTAATTGTTTTGTTTGTCTGATCTTTCTAGATGATGCGACCGAGAAGGATCTTTCTGACCTGGTGTCAGAGATGGAGATGATGAAGATGATTGGCCGGCACAAGAACATCATCAATCTGT[T/A]GGGAGCGTGCACACAGGATGGTGAGGGATTTATTTTCACTATAGAAAGCCTACATTATCAGTCCTCTAAATCATCAACATGATCAAAACTTTGCTGAAAAACCTGTTCCACACAACCAACTGCACGCCTTTGTCATCTGATTAATTGTTTATAGCTTATTAGCAAGTAATCATCTGCCTTCAGCTCAGGATTCACACATGCATTTTGCTATAAAATATCTACTGATTTTAATAAAGTAAATGAAGTAAATATTTAATATTTCAGAAATATTTCCAAGTAAACTAAATCAAATTATAAAAAATAAGTAAAAATCAGGCTTTTGAGTCATTGTTTTGCTTTCTATAATTGTTTTGCCCTCACAAAAAAAGCAATACTTGGAAGCTATATTTCAAAATAATGCATTTTACTGTCATCTTAAGACATTTTATTGGTTGATATAAAATTGCAATTAATATCTATACAGTTTATGTTGGTAGTCTGCTATACTTTTATATTTAAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa24945
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000007408 Essential Splice Site 554 817 12 18
ENSDART00000080914 Essential Splice Site 552 815 12 18
ENSDART00000080916 Essential Splice Site 577 840 11 18
ENSDART00000098269 Essential Splice Site 488 751 11 17
Genomic Location (Zv9):
Chromosome 13 (position 46933157)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 46185508
GRCz11 13 46321973
KASP Assay ID:
554-7846.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGCCGGCACAAGAACATCATCAATCTGTTGGGAGCGTGCACACAGGATGG[T/G]GAGGGATTTATTTTCACTATAGAAAGCCTACATTATCAGTCCTCTAAATC
Long Flanking Sequence:
AGTGTACAACAGCAGGCATGTCTAAACTCGGTCCTAGAGGGTCGGTGTCCTGCAAAGTTTAGTTCCAACCCCAGTCAGACACGCCTTGGCTAGCTAATCAAGCTCTTACTAGGTTTTCTAGAAACATCCTTGCAGTTGCCTAAGGCAAGTTAGAGCTAAAATCTGTAGGACACCAGCCCTCCAGGACCGAGTTTGGACACCCCTGATCTACAGTGTAAACCCAGAACAATGAGAAGAGTTGTATCCCATGATAAGACGAAGCTTGCAGCCAAGCATGCAGTTCCCTAGTACTACTTTACAATGTCATATGATCTCAGCTGAGCAGGAAATAGGAAGAATGGCTTTTTCTGAATGAGGTTTAATTGTTTTGTTTGTCTGATCTTTCTAGATGATGCGACCGAGAAGGATCTTTCTGACCTGGTGTCAGAGATGGAGATGATGAAGATGATTGGCCGGCACAAGAACATCATCAATCTGTTGGGAGCGTGCACACAGGATGG[T/G]GAGGGATTTATTTTCACTATAGAAAGCCTACATTATCAGTCCTCTAAATCATCAACATGATCAAAACTTTGCTGAAAAACCTGTTCCACACAACCAACTGCACGCCTTTGTCATCTGATTAATTGTTTATAGCTTATTAGCAAGTAATCATCTGCCTTCAGCTCAGGATTCACACATGCATTTTGCTATAAAATATCTACTGATTTTAATAAAGTAAATGAAGTAAATATTTAATATTTCAGAAATATTTCCAAGTAAACTAAATCAAATTATAAAAAATAAGTAAAAATCAGGCTTTTGAGTCATTGTTTTGCTTTCTATAATTGTTTTGCCCTCACAAAAAAAGCAATACTTGGAAGCTATATTTCAAAATAATGCATTTTACTGTCATCTTAAGACATTTTATTGGTTGATATAAAATTGCAATTAATATCTATACAGTTTATGTTGGTAGTCTGCTATACTTTTATATTTAAAAAAAAAAACATTTATTTATATTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa42296
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000007408 Nonsense 597 817 13 18
ENSDART00000080914 Nonsense 595 815 13 18
ENSDART00000080916 Nonsense 620 840 12 18
ENSDART00000098269 Nonsense 531 751 12 17
Genomic Location (Zv9):
Chromosome 13 (position 46931006)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 46183357
GRCz11 13 46319822
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGGAGTATTCCTATGATATAGCCCGCGTATCAGATGAGCCTCTCACTTTC[A/T]AAGATCTGGTCTCCTGCACTTATCAAGTTGCCCGTGGCATGGAGTATTTA
Long Flanking Sequence:
GGTACCTCAAAGGTACTTTTTAGTTACATTCTGGCACTAATATGCACCTTTGAGGTACCACTGTGGACCCTTCAGGTACAAATTTGTAACTTTTGAAAAGGTACTGCCCCAGTAACAGCTCCTGTACCTCTATTTTCGAGAGTGTGCTGCATAAAACAATTGCTGAATAAATTGGTGGTTCATTCCGCTGTGGCAACCCCAGATTAATGAATGGAGTAAACCGAAAAGAGAATGAATGAATGAATGAATAAATAATAGTAATAATTATAATACAGGACTGTACATTCATTCAGATGGTTTGTAATAATGATTCTGACTAATAGTAATGTAATAATGATAGTAATAATGACTCTCTTTCTCTTTCTCTCTCAGGTCCATTATATGTCATTGTTGAGTATGCATCTAAAGGGAACCTCCGGGAGTATCTGAGGGCCCGGCGGCCCCCAGGAATGGAGTATTCCTATGATATAGCCCGCGTATCAGATGAGCCTCTCACTTTC[A/T]AAGATCTGGTCTCCTGCACTTATCAAGTTGCCCGTGGCATGGAGTATTTAGCCTCTCAGAAGGTATCAGCACCTGCACAAAACACAATAACACCATTACATCTACATACATGTCTCTTTCATAGGCCTTTAATTGTTGGGATGTTTCTAATTTGCATTGCATGTAAAATTGCAACTGTGATCTAGCCGGGGCTCGAACCAGCGACTTTCTTGATGTGAGGTGAAAGTGCTAACCACTTAGCCACTGTGCCACATATTATTTGTATTACTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATATTACTATTATTATTATTATTATTATTATTGTTGTTGTTGTTGTTGTTGTTGTTGTTGTTGTTATTATTATTGTTATTATTACTAATATTAATTATTGTATTATTTAATATTATTATCGTTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATATTATTATTATTATTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa35586
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000007408 Nonsense 710 817 16 18
ENSDART00000080914 Nonsense 708 815 16 18
ENSDART00000080916 Nonsense 733 840 15 18
ENSDART00000098269 Nonsense 644 751 15 17
Genomic Location (Zv9):
Chromosome 13 (position 46917145)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 46169496
GRCz11 13 46305961
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCACTCTCGGCGGTTCTCCGTATCCTGGAATACCTGTCGAGGAGCTCTTT[A/T]AACTATTAAAAGAGGGTCATCGCATGGACAAACCTGCTAACTGCACCAAT
Long Flanking Sequence:
TCGCTAATGTTTGTTTTGGCAGGACAATATGTGTCATTGTAGCGTTTCGAGGAGGACAAAAGCCAGCTTTGAGAGTCCAGAGCCATTTGAGTCGTCCTACAATCTGAATAACTTTGCAGAAAGACTCCATTGAGGCGTTAACAGCTACTGCGTTGTTAGCGCCAACAATTATATTAAGATTTCTTTTTTGGAAAGGCTTCATTACATGGTTTAGTCCTCATCCAAATTTTTGGAGATGGTACCACATAGGAGACTGGAGTCTGTTGCTCCCTTTGACGGCGAATAACTGCATTAAAGGCTCAACTGTTTACAGTCTAAACATGGATTGAAAGTGTCATCTGAAGCACAAGTGTTTGCTGTGTGTCGTACTGGTAAAATGATCTCATCTGTGTGTGTGTGTTTTTTTTGTCTCTTCCAGCTGGTCGTTTGGGGTTTTAATGTGGGAGATCTTCACTCTCGGCGGTTCTCCGTATCCTGGAATACCTGTCGAGGAGCTCTTT[A/T]AACTATTAAAAGAGGGTCATCGCATGGACAAACCTGCTAACTGCACCAATGAGTTGTGAGTGCTCATCACTTTTGCTACACAGATTTTATGATACACAGTTTGATGAAGGGATAGTTCACCCAAAAATGGAAATTCACTACATTTACTCATCGTCACAGACCGGTTTGATTTTGTTAGATTTTTTTCTGCTAAACACAACTGAGAAACCCTAGTTGCCAATGGCTGTTTTTTCACAATATCATGTCGCGTTTAACAGAAAAAAAAAGAAATTCTTGCAAATTTAGAACCACTTGAGTGTAAGTAAATGGTGAGAATTTCTGAATTTAGCTATATTTGTGTCATATATATATATACACACACACACACACACACACACACACACACACACACACACACACACACACACTTACCGGCCACTTTATTGGGTACACCTGGTTGGACCCTTTTTTTTTGCCTTCAGAACTGCTTTAATCCTTCGTGGCATAGATTCAACAAGGTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa42295
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000007408 Nonsense 729 817 17 18
ENSDART00000080914 Nonsense 727 815 17 18
ENSDART00000080916 Nonsense 752 840 16 18
ENSDART00000098269 Nonsense 663 751 16 17
Genomic Location (Zv9):
Chromosome 13 (position 46915291)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 46167642
GRCz11 13 46304107
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACGAGTAAATAAATACAAACATGACGTGATGGTGTTTTGTTTCACAGGTA[C/A]ATGATGATGAAGGACTGCTGGCATGCCATCTCCTCCCACAGACCCACATT
Long Flanking Sequence:
GGTTGTGCGTGAAATCCCAGTAGATCAGCAGTTTCTGAAATACTCAGACCAACCCGTCTAGCACCAACAACCATAACAACCCCTTAAATCACCTTTCTTCCCCATTCTGATGCTCGGTTTGAATTGCACCAGATCATCTAGACCACGTCTGCATGCCTAAATGCATTGAATTGCTGCCATGTGATTGGCTCATTAGAAATTTACATTAAAGAGTAGTAGTGCAGGTGTACCTAATAAAGTGGCCGGTAAGTGAATACACATAAATATAAATATATACTTAAACTATGTATTTATGCACAATAGTAAAGTTAAAATACTAATTTATTCTCCACCACTGCTCAAAACTCTCTCTCGCTCTCTCAGTGAATCTGCACACACACACAGAGACTGGTCTGTGCATGTCTGATTACGCAAACGATTTCGTCACTCATGCTTTACACAACAGAGCATACGAGTAAATAAATACAAACATGACGTGATGGTGTTTTGTTTCACAGGTA[C/A]ATGATGATGAAGGACTGCTGGCATGCCATCTCCTCCCACAGACCCACATTCAAGCAGTTGGTGGAGGATCTGGACCGCATTCTCACTCTGGCAACCAACGAGGTGAAGCCAGCAAGCATTCACATACACCACACACAAAGATGCATGCATAAACACACTTAAAAGCATTCGCACTTTCCCTATAGCTCTGTGATTCATCAGACTGTGCCAACACTGGCTCCGGTTTGCAATATTTCGCAACAGGAAGTTGAACGGTTTTTACGGTCAGCATGCAGGTCGAGAGTTGCACGCGCTTGATTTCATCCAGGCTTTCACCGGTCATTGTGTTAGCGTTGCTCAATTGTCAGATCAATCCCTACTAGATGATTTTTTTCCCCATTCACTAGCTGTCATCTGCTATATCCTTGCGGCCGATTGAGGGATGGAAATCTGTCAGAACTTGTCGAAATGGGGGATTGAGCCGTGGAAGCGAGATGATGCCAAAAGCTCCGGCGTTTTGA
Associated Phenotype:
Not determined