Busch Lab

ZMP

comtd1

Ensembl ID:
ENSDARG00000078918
ZFIN ID:
ZDB-GENE-030131-1072
Description:
catechol-O-methyltransferase domain containing 1 [Source:RefSeq peptide;Acc:NP_001157280]
Human Orthologue:
COMTD1
Human Description:
catechol-O-methyltransferase domain containing 1 [Source:HGNC Symbol;Acc:26309]
Mouse Orthologue:
Comtd1
Mouse Description:
catechol-O-methyltransferase domain containing 1 Gene [Source:MGI Symbol;Acc:MGI:1916406]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa8488 Nonsense Mutation detected in F1 DNA Not yet available
sa1067 Nonsense F2 line generated Not yet available

Mutation Details

Allele Name:
sa8488
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000108921 Nonsense 94 238 4 7
ENSDART00000137776 None None 119 None 3
ENSDART00000148269 Nonsense 142 286 4 7
Genomic Location (Zv9):
Chromosome 13 (position 17729464)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 17549499
GRCz11 13 17680491
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AAACGCTCATTTTGTACCTCTCTTAGGTCTGTACACTGGATACAACGCCT[T/A]RAGTCTGGCTCTGGTAGTTCCTGAGAATGGACGTGTGGTGGCCTGTGAAA
Long Flanking Sequence:
CATGTTCAAAGTCACTTAAATCACCTTTCCTCCTCGCTCTGATGCTTTGCCATTCTGACCATCTTGTCTTCACCATGTCTGCATGCCTAAATACATTGAGTTGCTGCCATGTGTTTGGCTGATTAGAAATTTGTATTAACAAGCAGTTGGTACCTATTAAAGTGGCTGGTGAGTGAATGTAATTGAATATTTCATGAGAACTATGGAGGACACTAGATGTCAGTAGAGGTGACAATTCTGTACAATAACCCTTTTCACATGGATATTTTTTTGTATATTTAAAGAGAACTATGGAGGATGCCAGAAACGTCATGATGGTGGCATCTGAGCAGGCTCAGCTAATGGCTAATCTGGCTAAACTCATAGAAGCCAATAAAACTATTGAGATTGGTGAGTGGAAGGAGCAAAATTACAAAAAATTATGTGCTTACATTCTTTTGGCTACCTGTAAAACGCTCATTTTGTACCTCTCTTAGGTCTGTACACTGGATACAACGCCT[T/A]GAGTCTGGCTCTGGTAGTTCCTGAGAATGGACGTGTGGTGGCCTGTGAAATTAATGAGGATTATGTGAAAATAGGCAAGCCATTTTTTGCAGAGGTAAAGCAAAACGTACAAAGTTTGTAAAGCTGCATTTGGTTGCAACTGAGGTGATTTGTTTGATTCGGACACATCATTGCTTTCATCAACTGTATCTGTTAAGTTGCTCCTCAACAAACACCTACACAATTCTCAATTTCAATATTGATTGCTGCCTGTCATTGTAAGGACAGCGTCATCAGTATATAAAGCCAGCTGGGCAGATGCAGAAATGTCCATCAAGCTGATTGCTGACATGGACAGATTGGGGGATTCTACATTTGGGTGCTGATATTTGCACAAAATTAAATTGCAAAGTGCTTCATCTACATTTTGTCCATCCTATAAGTAAAAATAGGAATGTGTGCATAAATGAATAACCTAATGAAGATTATCACCTATCATAGAAGTAATATTATATGTCTAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa1067
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000108921 Nonsense 120 238 4 7
ENSDART00000137776 None None 119 None 3
ENSDART00000148269 Nonsense 168 286 4 7
Genomic Location (Zv9):
Chromosome 13 (position 17729541)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 17549576
GRCz11 13 17680568
KASP Assay ID:
554-0970.1 (used for ordering genotyping assays)
KASP Sequence:
ATGGACGTGTGGTGGCCTGTGAAATTAATGAGGATTATGTGAAAATAGGC[A/T]AGCCATTTTTTGCMGAGGTAAAGCAAAACGTACAAAGWTTRTAAAGCTGC
Long Flanking Sequence:
TCTGCATGCCTAAATACATTGAGTTGCTGCCATGTGTTTGGCTGATTAGAAATTTGTATTAACAAGCAGTTGGTACCTATTAAAGTGGCTGGTGAGTGAATGTAATTGAATATTTCATGAGAACTATGGAGGACACTAGATGTCAGTAGAGGTGACAATTCTGTACAATAACCCTTTTCACATGGATATTTTTTTGTATATTTAAAGAGAACTATGGAGGATGCCAGAAACGTCATGATGGTGGCATCTGAGCAGGCTCAGCTAATGGCTAATCTGGCTAAACTCATAGAAGCCAATAAAACTATTGAGATTGGTGAGTGGAAGGAGCAAAATTACAAAAAATTATGTGCTTACATTCTTTTGGCTACCTGTAAAACGCTCATTTTGTACCTCTCTTAGGTCTGTACACTGGATACAACGCCTTGAGTCTGGCTCTGGTAGTTCCTGAGAATGGACGTGTGGTGGCCTGTGAAATTAATGAGGATTATGTGAAAATAGGC[A/T]AGCCATTTTTTGCAGAGGTAAAGCAAAACGTACAAAGTTTGTAAAGCTGCATTTGGTTGCAACTGAGGTGATTTGTTTGATTCGGACACATCATTGCTTTCATCAACTGTATCTGTTAAGTTGCTCCTCAACAAACACCTACACAATTCTCAATTTCAATATTGATTGCTGCCTGTCATTGTAAGGACAGCGTCATCAGTATATAAAGCCAGCTGGGCAGATGCAGAAATGTCCATCAAGCTGATTGCTGACATGGACAGATTGGGGGATTCTACATTTGGGTGCTGATATTTGCACAAAATTAAATTGCAAAGTGCTTCATCTACATTTTGTCCATCCTATAAGTAAAAATAGGAATGTGTGCATAAATGAATAACCTAATGAAGATTATCACCTATCATAGAAGTAATATTATATGTCTATGAAAAGCAAAGAATCAAATGTTTTATTAAGTTAGAACAATTAGAACCTATAAGTGCAAATTGTCTTTGTTTTAGGCT
Associated Phenotype:
Not determined