Busch Lab

ZMP

yrk

Ensembl ID:
ENSDARG00000004378
ZFIN ID:
ZDB-GENE-030131-9517
Description:
Yes-related kinase [Source:RefSeq peptide;Acc:NP_997946]
Human Orthologue:
FYN
Human Description:
FYN oncogene related to SRC, FGR, YES [Source:HGNC Symbol;Acc:4037]
Mouse Orthologue:
Fyn
Mouse Description:
Fyn proto-oncogene Gene [Source:MGI Symbol;Acc:MGI:95602]

Alleles

There are 2 alleles of this gene:

Allele Name Consequence Status Availability
sa36915 Nonsense Mutation detected in F1 DNA Not yet available
sa10663 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa36915
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000102394 Nonsense 354 525 8 11
ENSDART00000102395 Nonsense 357 528 8 11
ENSDART00000136695 Nonsense 354 525 10 13
ENSDART00000147290 None None 27 None 2
ENSDART00000148287 Nonsense 357 528 10 13

The following transcripts of ENSDARG00000004378 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 19 (position 45162019)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 43825984
GRCz11 19 43421581
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCTTATTGGACTTTTTGAAAGATGGTGATGGCAGAAATTTAAAATTGCCT[C/T]AACTTGTGGACATGGCAGCACAGGTAATGTTTACTTTCCCATTTTTTTCA
Long Flanking Sequence:
ATGATAAACTGGTTCAGCTTTATGCTGTGGTGTCCGAGGAGCCTATCTACATCATCACCGAGTTCATGAGTCAAGGTCTGGAGCGATATCAATTCAGTTCACGTTTATTCCTACAGCATTTTTTACAGTATCGTTTCAAAGCAGATTCACAAAACGGTGCACATTATTGCTTCACAATCCATTTCGGAGAAGTGAAAGTTATTAGTTGCCATAACTTTAAAGGTGACTAATTAACTAGTAATTAGTAGCTTTAACATCTAAAATGATAAACATAGTTAATGTGCAGTTAGGTGATGTCAATTTATACATGTTTAATGAATATGATGATATCAGCGAGAACAAAAACAACTGGGGTTGAGGTGGATTTAGAGGGTTTTGTATCTAAACTCTTCAAATATTATGTTATAATTAGGCATAATTTTTTTTATTTATGCTTGTGTGGTTTAGGAAGCTTATTGGACTTTTTGAAAGATGGTGATGGCAGAAATTTAAAATTGCCT[C/T]AACTTGTGGACATGGCAGCACAGGTAATGTTTACTTTCCCATTTTTTTCATCATATTGTGTTTTTTAAGCATTTTAAGCTTTGAAACCAACCAGCTACGATGAGAATCACAACATTACACATTTAAAGTACATGGAAATAGTTTTTGAAAGCACAAGGACACTTGATTACATCATTTTGGGCTGTCAGTGAAAATCTAATAGATATCTAAGAATATAGCCCAAAACTAGACTAGTTGTCAAATAGACAGATTAGACCATTGTTTCTCAACTGGTTGGTCACGGTATTATTTTCAGTGGGTCGTGTTTGTGGTCAAAAAACAACAAAAGATCAACTTTTTACTTCTTTTTCCTTATACTGGACTTTTATTTTGAAATGCATGCGCGACAAGCGTACAGTTTGACTTGTGAAATTTCATTTAATTATTGCAACAAATATGTCGGAGCGCAAGTACGACCCCGAATGTGTAAAGTATGGATATATATAATGATGACAAAAAAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa10663
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000102394 Nonsense 407 525 9 11
ENSDART00000102395 Nonsense 410 528 9 11
ENSDART00000136695 Nonsense 407 525 11 13
ENSDART00000147290 None None 27 None 2
ENSDART00000148287 Nonsense 410 528 11 13

The following transcripts of ENSDARG00000004378 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 19 (position 45159390)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 43828613
GRCz11 19 43424210
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGGTCTGTAAGATTGCAGATTTCGGTCTGGCTAGACTGATCGAGGACAAC[G/T]AGTACACAGCTAGACAAGGTCAATCCATGCTCCAAACTTGATCCTAATCT
Long Flanking Sequence:
ATCAGCTGCCGACAGGAAGTTCTCAGCATTCTCCTTGCGCATAAACGCAAAGCATAATGGGTAATTTTGCGTTCTAAGAAAAAGGTCTATATGTGGTCATTCACTTCTGTTTATTTGATGACTGCTCTAGTTTTGGCCTATTCTTAAATGTCCATTAAATTTTCACTGACAGCCCAAATTTAGCCATGTTTTAGACAAGATGAATATGTTTAGACATCTATTAGAGATCTTTTAAAAAACCAAAAATGTTTGCTGTTTATTATGTTTTGTTTCCATTAAACAGAAATTGGGGAAAATATATACAGGGGGGCTAATAATTCAGGAGGGCTAATGATTCTGACTTTGACTGTATTTCTTTGTTTCAGATCGCTGCCGGCATGGCCTACATCGAGCGGATGAACTACATCCACCGAGACCTGCGAGCTGCCAATATCCTGGTCGGAGACGGTCTGGTCTGTAAGATTGCAGATTTCGGTCTGGCTAGACTGATCGAGGACAAC[G/T]AGTACACAGCTAGACAAGGTCAATCCATGCTCCAAACTTGATCCTAATCTACTCAGCATATTTCTTCCATTTGCCCGAGTCTCTTCCTTTATTCGAGACTATCAGATGTTATTTATCTCCTCCTCGGCCTCTATTCGATTTCATTCCAGCTCATTTTGTTCTAATTCTCCTTTTACTGCGGTTCAATTTCCATCTTTCATTGCTCTATTTTAGGATGCTTTATCTCAGTCCTCCGGTTCAGCGCCTTTTCACTTGATCTGCAATTTTCATAAATCATTAGGAAATGTGCTGAAGTGATTGTCTCGATGCTGGTGTTGTAGGAGCGAAGTTTCCCATTAAGTGGACTGCACCGGAGGCGGCTCTCTATGGTAAATTCACCATCAAATCAGACGTATGGTCTTTCGGCATCCTGTTGACGGAGCTGATTACCAAGGGCAGAGTGCCATATCCAGGTGCGTCACAAATCTGTGTTTGTTTGTTGAATGAAACTCAATGCAAGA
Associated Phenotype:
Not determined