ZMP
exosc2
Ensembl ID:
ZFIN ID:
Description:
exosome complex exonuclease RRP4 [Source:RefSeq peptide;Acc:NP_001017572]
Human Orthologue:
EXOSC2
Human Description:
exosome component 2 [Source:HGNC Symbol;Acc:17097]
Mouse Orthologue:
Exosc2
Mouse Description:
exosome component 2 Gene [Source:MGI Symbol;Acc:MGI:2385133]
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa33781 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa40616 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa10662 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa33781
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000032260 | Essential Splice Site | 2 | 254 | 1 | 9 |
Genomic Location (Zv9):
Chromosome 5 (position 75251879)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 71353020 |
| GRCz11 | 5 | 72137526 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACCTGGTTGTGCCTGGAGATGTGATCACCTCCGACACGGGCTTCATGAGG[T/C]ACACAGACATTAATAACTGGTATTAACTGAGCTGTTGTAGAATAAATGTG
Long Flanking Sequence:
TGATTATTTATATAATCTCATTCTTTTAAGAACCTGTGTTTACACAATAAAAGAATAACAAAAATAAATGTAGAAAGCAAATTGGTTCTGAAAAGTATAAAATTATTTTGTTAGAGCATATAATGTTAACTTAATGTTTTAATGTATTAAAGTTTTGCTATATTGTCATTTAAAATGTTAAATATAAAAAGTCTCTTAATTCTCGTTACAAAATAAAACCTCACACATTGTATAACACGAACTTAAATCGTTATTTAATGACCAAATTCAGATGATTAGATGCTCAAACCGAACACGAACACAGTCGGGCTTTTATTATGAAGTGGAGCCGTGCTCGCCGCCATATTGCCCGGCTATAGTGTTGTTGAAGCATGGCGGTGGAGATGCGGCTTCCAGCGGTTCACAAACACGTTTCCCTGAAAACAGGACAGAGTTCCCGCGAAGACAAACACCTGGTTGTGCCTGGAGATGTGATCACCTCCGACACGGGCTTCATGAGG[T/C]ACACAGACATTAATAACTGGTATTAACTGAGCTGTTGTAGAATAAATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGGAGTGAACTCGTTGAGACCTGCAGTCTGTCAGTCTGTAGCGGACTTGATTGAGAACTCAAGTTAGTGTATGTAGTGTATTTGTTCAGTGTTGGAGAAAGTTACTTTACTGACAGACTCTTCTGGAAAGTAACTAGTTGCGTTACTTTTTACGGTGACGCGTTACGTTACTTTTAAAATACATTATTTACATGTGTATTGATTGAGGTAAAGTTGGTTTGTATTTGCACGTTCGTTCATTTTTGAACGGTGATAACTTGTGACACGTTGCCTGTATTGTACTTTGAGTATTCGGTCT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa40616
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000032260 | Essential Splice Site | 36 | 254 | 2 | 9 |
Genomic Location (Zv9):
Chromosome 5 (position 75254379)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 71355520 |
| GRCz11 | 5 | 72140026 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAGGTGGAGCGAGTCAACAAACTCATCTGTGTGAAACCGCTGAAGACCAG[G/A]TGCACACTGACTTACACTAACGCCACAGCACAGGTCTCAAACTAAATTCC
Long Flanking Sequence:
TCATAGCTTGTGATGTTTATAGTCTGCATAATCGAAAAGGTCTAAAAAACTGTAATATTATTACTGATGTGTCTAGCTCCTACAAAGCCGGACTGTGTTTCAGCAATCAGCTGAAATCTTTAATCTGTTAGCAAATATCAAGGCTAAAATTTTATTGTCAATAGTGATGAGCGTGATTGCACGCTAATTATCTAAATTTTAGATCAATGCATTCATTATACATCCAAAGCAAAGGCTTTAATTAATTAGTAGAAAGAGCATATAAATGTGCCGGTCAATCCATCATCGCTGGGGTGAAACAAGAGCCCTTTAAATTTTGCTTTACTGTCTTATTGAATGTGAAATTCCAATTGTGCGAAGATAAAAACCGTTTTCATCTGACTTCACCTCGTCCTCAGGGGTCACGGCACCTACATGGATGAAGACAGACTCACCGCTTCAGTGGCAGGACAGGTGGAGCGAGTCAACAAACTCATCTGTGTGAAACCGCTGAAGACCAG[G/A]TGCACACTGACTTACACTAACGCCACAGCACAGGTCTCAAACTAAATTCCTGGAGGGCCGCAGCTCTGCACAATGTGCCCCAACCCTGATCAACTGTGTTTGATTGGCTTGGAGCAAAACTGTGCAGAGCTGCGGCCCTCCAGGAGTTAGAGACCTGTGCACTACAGTATAGCACACTGCACTTCACTAATGTATAATGCTGTGGTAATACTGTGTTCTAGATGTGATGTTCTCCTCCTGCAGGTATAACGGAGAGGTGGGTGATGTGGTTGTGGGCAGAATCACTGAGGTCAGTGGTGTTCAGTAGTTTATGTATAAAATCTCTCGTTGTTGTTGTTGATGATGATGATGATGATGATGATGATGATGATGATGATGTGCATCTCTAAATGTTAAGGTGCAGCAGAAGCGATGGAAAGTGGAGACTAACTCGCGTCTGGATTCAGTGCTGCTGCTGTCGGCGGTCAATCTGCCTGGAGGAGAGCTGGTGAGCTGGCAAC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa10662
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000032260 | Nonsense | 247 | 254 | 9 | 9 |
Genomic Location (Zv9):
Chromosome 5 (position 75257541)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 71358682 |
| GRCz11 | 5 | 72143188 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AAGACATCCTGAAGCCRGAGATCATGGAGGAGATTGTTCTGGAAACACGG[C/T]AGCGTCTGATGGAGCATGAAGGCTGAAACACCGCTCTATATATAATGMAT
Long Flanking Sequence:
ATGCATGCATGCATGCATGTGTGGGTAAGTGGGTGTGTGTGTGTTTGGGATAGTGTGTGTGTGAATGATTGGGTGTGTGTGTCTGTACTGGTTTTGGTGGTTTACAGGGACAGAAATGTGTATAATGTTGTGTGTGATCTAAATATAACAACTTGTGCGCGTGTGTGTGTGTGTGTGTGTGTTTGTGTGTGCGTGCGCGCAGCCTGTGTCTCTGTCGGATCGTGAGGTGGTCTCTAGGCTCAGGAACTGTCTCCTGGCTCTGGCCAATCAGAAGGTGCTGCTGTTCGACACCAGTGTGCTGTACTGCTATGAGGCGTCACTGCAACACCAGGTCTCAACACACGTCTGTCTGTCTGTCTGTCTGTCGCTTTGACTGTCTGACAGTCTGTCTGTCTCTAAGCGTGTGTGTGCAGCTCTTCATTCTCAGTATCTTTGCTGTTCTCCAGATTAAAGACATCCTGAAGCCGGAGATCATGGAGGAGATTGTTCTGGAAACACGG[C/T]AGCGTCTGATGGAGCATGAAGGCTGAAACACCGCTCTATATATAATGCATATAACACACACCACATTATTCATATTTTGTAATAAATTTGTTATAACACCCAAAGCGTGTGTGTGCGTGTGCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTGATCATTCTCTCAACCTGAAGAGTGCTGGAGAAACACACATTGACTTTCATCGTCTTTATTCCTGCTATTGAAGGCAGCGGCAGCATTCTTCAGAGTATCTTATTTTGTATTCGACAGAAGAAACCCATAGGTGTTTAGAAGCAGAGCAAATGAGGATTAGGGTGGAACGGTGGCTCAGTGGTGTCGCACTGTGTGCTCACAGCAAGAAGGTCTCTGGTTTGAGTCTCGGCTGGGTCAGTTGGTGTTTCTGTGTGGAGTTTGCATGTTCTCCCCGTGTTGGTGAGGGTTTCCTCC
Associated Phenotype:
Not determined