Busch Lab

ZMP

zgc:123272

Ensembl ID:
ENSDARG00000042727
ZFIN ID:
ZDB-GENE-051113-108
Description:
defects in morphology protein 1 homolog [Source:RefSeq peptide;Acc:NP_001032490]
Human Orthologue:
DEM1
Human Description:
defects in morphology 1 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:26115]
Mouse Orthologue:
Dem1
Mouse Description:
defects in morphology 1 homolog (S. cerevisiae) Gene [Source:MGI Symbol;Acc:MGI:1920422]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa39046 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa10679 Nonsense Available for shipment Available now
sa10418 Nonsense Available for shipment Available now
sa10566 Nonsense Available for shipment Available now
sa39045 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa39046
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000062695 Essential Splice Site 12 229 1 6
ENSDART00000129154 None None 394 None 6

The following transcripts of ENSDARG00000042727 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 15 (position 24447191)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 25158378
GRCz11 15 25093643
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TAGTTTGTTGTGAATGTGGTCATGTGACTTTATTTTCTGGACACAAGCGG[G/T]TATTGTTGAGTTATATAAGTGTTCGTGTCTCATCTTTTTTCTTCCATGTT
Long Flanking Sequence:
GCATGGGTAATAACTGCTTTCAGAATGCTTATCCATACACAGACTGTCTTACCGTGCACGATGCAAACGGATGAGCCAATCGGATATATTTTTAGAGAGGTGGGCGGGACTTAGATTATCAGCAAATGAAATACAAACATTAGCAGCAAGCGAAGAAAGATGTTGTTGACAGAGGCGGGGCATTGACGGAAGTTGTTCGGGCATGTCTCATGTAAACAATTCAAACTTAAAATAAAAACAAATTAAAATACAAACTAGCATCGTGTTTAAGTTCCTGCAGCATTGGTGTAAAGTGCACAATGGGCTGAGAGAACAGTTTGAGTTTGCTTTTATGATGGATGCGTCTAGATCACAACAACCGCTGGATGCCTGGGACGACATTAGCGACTCTGAGTTTCTTAACATCCCTTCCGACGAAGAAAGTATAGGTAAAACATTGTGCAATTGTGGTAGTTTGTTGTGAATGTGGTCATGTGACTTTATTTTCTGGACACAAGCGG[G/T]TATTGTTGAGTTATATAAGTGTTCGTGTCTCATCTTTTTTCTTCCATGTTTGCATTTAAACACATGTGTGTTGTTTTGTTTACATGTTATCTCTTTTAAGAGTCCCAGCTTCCTCTTATCGGAGAAACTAAAGGTAAACATTCAGTGAACTTGGACAAACCCAGTTCATCTTCATCATTTCACAAGTAAGTTTTTCATGTGGTGGTGCTGCTGAGAGGAACATTTTTTGTAGATGGTGATTTTATATGTGAGAATGTTAAATTAATACAAACGTGAAATGTTTGCTTAAATTCAAACAACCTTTGTGAAAATAAAATGTGAAAAATATATATGAAATAATCAGTGCAACTAATATGTCATAAATAGAACACTTATTTCGGCTTGTACTTAGTAAATTTATTCAATAATAAGCAATAATTCAAAATTGTATAATACTTTAAATAAAACAAAATGGGTAAACTTTGTAGTTTAAAGGAAAGTGACAAAGTGGAATTTTTTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa10679
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000062695 Nonsense 228 229 6 6
ENSDART00000129154 None None 394 None 6
ENSDART00000062695 Nonsense 228 229 6 6
ENSDART00000129154 None None 394 None 6
ENSDART00000062695 Nonsense 228 229 6 6
ENSDART00000129154 None None 394 None 6

The following transcripts of ENSDARG00000042727 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 15 (position 24440761)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 25151948
GRCz11 15 25087213
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TYATGTCTTTCGTCTGTTTTCAGGGTTTTTTTCTTGTAAGGCAMGGCTTT[C/T]GAAAATGATGAYATGAGACTCTGCTGGGTAGCTGCGCTGGTTTACTAACA
Long Flanking Sequence:
ATGAAAAATCTATTTTAGTTTCTCAAAATAGCAACGCGCCAGCAATGCACCTCAGAACGCCTTCCTTTTTAGACCCTTTTTTAGAAACGCCTATGGATGCACATATGAGCGCTAATGCATTTGCTATTTAAACAGCGTAGCGCAACGCCTCAAAACGACTCTTGTGCCAAGCTTAAACTACCAAACAAGTATTGCGCTGCGCCTTGCGCCACATTGCACCTGGTGTATAGGGCCCTATGTCTTGAGCAACTGATTTCTCCTCTGTGATTATGTCCTTTAAATAGGTTATATAAAGGCTGGTTATTTTACCGTCGATGAGAGACAATAGTGGTATACAGATTTCAAAAGAAATATTTTAATATTAAAAGGAAACATAAGCTTGACATCAAAAGATCCGTTTACAGCAAGCATTAAGTGTTCATTGAGATGTGTTTGGGATTGTGTCCTCTGTCATGTCTTTCGTCTGTTTTCAGGGTTTTTTTCTTGTAAGGCACGGCTTT[C/T]GAAAATGATGACATGAGACTCTGCTGGGTAGCTGCGCTGGTTTACTAACACTTGTTTAGGTCTGTACTTTCTTAGCATCTTCATAAGGGTGGTCTTGTTTTAAATGGTGAAACAGGTTTGTGGTGTTGGCTGCTTTTGATGACACGAGACGTCTGCGCAGTTTGCGGTGCACGTTACTCTGTTTTGTGTCGGATAGCAAAAAACTAATTAGCTCATGACTGAGGTCTAGTGACGTTTCTTGTCAACAATGTCTGTGATTGACCTTTTTTTTACCTTATTTCTTTGTTACTTCTTTCAGTGCAACTAACACTGTATGGCTGTAAACTTGTAAGGCGTGCGGCATCCGGAAGGGCACGCTGTAAAATGCTTGCGCAACGTTACGCATAGTGCGTAAATATTATCGAGCAATTATCGAACTGTCATTATCGTTTTATCGAAAAATTTTATATCCTGATAATTATCGATATCGAATTATCGCCCAGCTCTAAATTGAAGGAACC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa10418
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000062695 Nonsense 228 229 6 6
ENSDART00000129154 None None 394 None 6
ENSDART00000062695 Nonsense 228 229 6 6
ENSDART00000129154 None None 394 None 6
ENSDART00000062695 Nonsense 228 229 6 6
ENSDART00000129154 None None 394 None 6

The following transcripts of ENSDARG00000042727 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 15 (position 24440761)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 25151948
GRCz11 15 25087213
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TYATGTCTTTCGTCTGTTTTCAGGGTTTTTTTCTTGTAAGGCAMGGCTTT[C/T]GAAAATGATGAYATGAGACTCTGCTGGGTAGCTGCGCTGGTTTACTAACA
Long Flanking Sequence:
ATGAAAAATCTATTTTAGTTTCTCAAAATAGCAACGCGCCAGCAATGCACCTCAGAACGCCTTCCTTTTTAGACCCTTTTTTAGAAACGCCTATGGATGCACATATGAGCGCTAATGCATTTGCTATTTAAACAGCGTAGCGCAACGCCTCAAAACGACTCTTGTGCCAAGCTTAAACTACCAAACAAGTATTGCGCTGCGCCTTGCGCCACATTGCACCTGGTGTATAGGGCCCTATGTCTTGAGCAACTGATTTCTCCTCTGTGATTATGTCCTTTAAATAGGTTATATAAAGGCTGGTTATTTTACCGTCGATGAGAGACAATAGTGGTATACAGATTTCAAAAGAAATATTTTAATATTAAAAGGAAACATAAGCTTGACATCAAAAGATCCGTTTACAGCAAGCATTAAGTGTTCATTGAGATGTGTTTGGGATTGTGTCCTCTGTCATGTCTTTCGTCTGTTTTCAGGGTTTTTTTCTTGTAAGGCACGGCTTT[C/T]GAAAATGATGACATGAGACTCTGCTGGGTAGCTGCGCTGGTTTACTAACACTTGTTTAGGTCTGTACTTTCTTAGCATCTTCATAAGGGTGGTCTTGTTTTAAATGGTGAAACAGGTTTGTGGTGTTGGCTGCTTTTGATGACACGAGACGTCTGCGCAGTTTGCGGTGCACGTTACTCTGTTTTGTGTCGGATAGCAAAAAACTAATTAGCTCATGACTGAGGTCTAGTGACGTTTCTTGTCAACAATGTCTGTGATTGACCTTTTTTTTACCTTATTTCTTTGTTACTTCTTTCAGTGCAACTAACACTGTATGGCTGTAAACTTGTAAGGCGTGCGGCATCCGGAAGGGCACGCTGTAAAATGCTTGCGCAACGTTACGCATAGTGCGTAAATATTATCGAGCAATTATCGAACTGTCATTATCGTTTTATCGAAAAATTTTATATCCTGATAATTATCGATATCGAATTATCGCCCAGCTCTAAATTGAAGGAACC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa10566
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000062695 Nonsense 228 229 6 6
ENSDART00000129154 None None 394 None 6
ENSDART00000062695 Nonsense 228 229 6 6
ENSDART00000129154 None None 394 None 6
ENSDART00000062695 Nonsense 228 229 6 6
ENSDART00000129154 None None 394 None 6

The following transcripts of ENSDARG00000042727 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 15 (position 24440761)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 25151948
GRCz11 15 25087213
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TYATGTCTTTCGTCTGTTTTCAGGGTTTTTTTCTTGTAAGGCAMGGCTTT[C/T]GAAAATGATGAYATGAGACTCTGCTGGGTAGCTGCGCTGGTTTACTAACA
Long Flanking Sequence:
ATGAAAAATCTATTTTAGTTTCTCAAAATAGCAACGCGCCAGCAATGCACCTCAGAACGCCTTCCTTTTTAGACCCTTTTTTAGAAACGCCTATGGATGCACATATGAGCGCTAATGCATTTGCTATTTAAACAGCGTAGCGCAACGCCTCAAAACGACTCTTGTGCCAAGCTTAAACTACCAAACAAGTATTGCGCTGCGCCTTGCGCCACATTGCACCTGGTGTATAGGGCCCTATGTCTTGAGCAACTGATTTCTCCTCTGTGATTATGTCCTTTAAATAGGTTATATAAAGGCTGGTTATTTTACCGTCGATGAGAGACAATAGTGGTATACAGATTTCAAAAGAAATATTTTAATATTAAAAGGAAACATAAGCTTGACATCAAAAGATCCGTTTACAGCAAGCATTAAGTGTTCATTGAGATGTGTTTGGGATTGTGTCCTCTGTCATGTCTTTCGTCTGTTTTCAGGGTTTTTTTCTTGTAAGGCACGGCTTT[C/T]GAAAATGATGACATGAGACTCTGCTGGGTAGCTGCGCTGGTTTACTAACACTTGTTTAGGTCTGTACTTTCTTAGCATCTTCATAAGGGTGGTCTTGTTTTAAATGGTGAAACAGGTTTGTGGTGTTGGCTGCTTTTGATGACACGAGACGTCTGCGCAGTTTGCGGTGCACGTTACTCTGTTTTGTGTCGGATAGCAAAAAACTAATTAGCTCATGACTGAGGTCTAGTGACGTTTCTTGTCAACAATGTCTGTGATTGACCTTTTTTTTACCTTATTTCTTTGTTACTTCTTTCAGTGCAACTAACACTGTATGGCTGTAAACTTGTAAGGCGTGCGGCATCCGGAAGGGCACGCTGTAAAATGCTTGCGCAACGTTACGCATAGTGCGTAAATATTATCGAGCAATTATCGAACTGTCATTATCGTTTTATCGAAAAATTTTATATCCTGATAATTATCGATATCGAATTATCGCCCAGCTCTAAATTGAAGGAACC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa39045
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000062695 None None 229 None 6
ENSDART00000129154 Nonsense 244 394 6 6

The following transcripts of ENSDARG00000042727 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 15 (position 24439108)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 25150295
GRCz11 15 25085560
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TACATCTGTTCTAAAACATGCATCTATTACTCAGGTGGGCCTGTATAAAT[T/A]GCTCTTTGATGGACTGGTCAGAGGGGAGATGAAAAAAAATCACATTTTCG
Long Flanking Sequence:
TTAATAATATTGTGTTGTTTCTCCTAAATAGTTTTAAGCATGTCTTAATTTTCCTATACCCTAGTAAAGCTACCCTATAGGACCTCTTTTATTGCAAAGAGATACAATCCAAAATATTTTTACAGCAAATTCTCCAAATTAAATTCCCTAATTAAGGAAAGTAAACTAAAGCAACGCATCCCTTTACATGATTTTCTGTTAATACAAAAACTATATCACATACATCACAAAATACTTTGTATTTAGTCAGGGAACAAAACTGCTAATGCTTGAAGACCCTTAAAGTAAACTTTTTCAGTTTTAAGTTACATTTTAAGAGATAAAAACATTTATATCTGATGGAAAAAAATCTTATAAATGGCATAAGTGTTTCAAATTCTTATGACCCCAACATATAAAAGCACATTTCTAGGTGACATTTCTGTCATGATCTGCTTTATATTGCATTTTTACATCTGTTCTAAAACATGCATCTATTACTCAGGTGGGCCTGTATAAAT[T/A]GCTCTTTGATGGACTGGTCAGAGGGGAGATGAAAAAAAATCACATTTTCGATCACCTCAAACTGCGTTCTGCTCAAATTCTCGGTGCAGGCGTCCAGGCTCATGCTAAAAACCTTGGGGTTCATGCCAGAACATTTGAGGAGCTGGTTGAAACTTTGCTTATAACAGTGTCATGCTCTGATCTTCCATGTATTGACCTGCTTCAGATTGAATACTTTCATCAAGGCTCTAATGGGCCCATTGGGACAAGAGTGGCTCCTTTTGATGAAGCCCAAATACGGGGAGAGCTTCAGGCTTATTTGTCCTACTGGACGGGACAGAGAGAACCTAAAGGGGTGGATATAGAGGAGGCCTGGAAATGCAGATCATGCCTGTATGAGGAGATCTGCGAATGGAGGAAGAACAGATTTACAGTTTCTGACCAACAAGCGGCTCATTCTAGCTCACACTTATGATTTTACAGATCATATTTATATATTTGAATGTGCAGTGTTAATTATG
Associated Phenotype:
Not determined