ZMP

ptpn11a

Ensembl ID:

ENSDARG00000020334

ZFIN ID:

ZDB-GENE-030131-5911

Description:

tyrosine-protein phosphatase non-receptor type 11 [Source:RefSeq peptide;Acc:NP_956140]

Human Orthologue:

PTPN11

Human Description:

protein tyrosine phosphatase, non-receptor type 11 [Source:HGNC Symbol;Acc:9644]

Mouse Orthologue:

Ptpn11

Mouse Description:

protein tyrosine phosphatase, non-receptor type 11 Gene [Source:MGI Symbol;Acc:MGI:99511]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa41576	Nonsense	Mutation detected in F1 DNA	Not yet available
sa10099	Essential Splice Site	Available for shipment	Available now

Mutation Details

Allele Name:

sa41576

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000081599	Nonsense	104	594	3	16

Genomic Location (Zv9):

Chromosome 10 (position 3442508)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	10	3434702
GRCz11	10	3435006

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CTGAAAGAGAAAAACGGAGACGTCATTGAGCTGAAATACCCTCTGAACTG[T/A]GCCGATCCCACCTCCGAGAGGTGAGCACATACATACCTCATTATCTGTCT

Long Flanking Sequence:

CGATACAAATGATAAATAAATTGCATTATCTATGTAATCAAGTTATTTTAGAACACTGAGGTCTGTAGTACACGCTGTCATACAGAGCTGTGGAGACATTGGCGTAAATTGTTATGGAATGTGTTTTTTTAATTGGACTTTGAGTCTTTTATAAAGTTTGATATTATGTGTTTTGTATAGTTTGGCTACATAAATGTATTTTAATAAGTTCAGATTTAATAAACAACCAAATATGCAAATTTGTACGGAATCATTTTTTAAAATCCATATTTTTTACTTAAAATTACTTAAATCTTCTTTCATTTTTTTTTTCATCTCCTCACTAGGCGAAATGGCGCTGTCACACACATTAAGATTCAAAACACAGGAGACTATTACGACCTGTATGGTGGAGAGAAGTTTGCCACTCTTGCTGAGCTGGTCCAGTATTACATGGAGCATCATGGACAGCTGAAAGAGAAAAACGGAGACGTCATTGAGCTGAAATACCCTCTGAACTG[T/A]GCCGATCCCACCTCCGAGAGGTGAGCACATACATACCTCATTATCTGTCTGTCCTTACATGACAATTTGGGATGAGTTGTGTTTTATAGGCTTCTCTTTATTGGCTGTGAACTTGAACAAACCTTTTCTGACTGTCCTGTCTTTTTTTTTGCAACCACAAGGTGGTTTCATGGTCACCTCTCTGGTCGTGAAGCTGAGAAGCTGTTGACAGAGAAGGGCAAGAACGGAAGTTTCCTGGTGAGAGAAAGTCAGAGTCACCCAGGAGATTTTGTGCTCTCCGTACGAACTGGAGATGACAAGACGGACACCAGCGATGGCAAACCCAAAGTCACACACGTCATGATACGCTGCCAGGTAACAAAAAAAATAAATCAAATGCATTATTAACTATGTGGTTTTATATTGTCAGCCTGTTTTTTTTTTATCAGATGTGGATTAAAATCGTCTAGATCCTTAATATTAAGTAGACAATTAGTGTGCTCAAGTTGTGTGGAATTACA

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa10099

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

T > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000081599	Essential Splice Site	534	594	13	16

Genomic Location (Zv9):

Chromosome 10 (position 3453382)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	10	3445576
GRCz11	10	3445880

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

MGTACAGCATTATATTGAGACTCTGCAGCGCCGCATAGAGGAGGAGCAGG[T/C]GTGTACACTTACAGTGGGGGAGATAAGTATTGAACACATAACCATTTATC

Long Flanking Sequence:

AGAACACATGAGAAAGAACGAACAAGAAAGAAAGTACACGAGGAAAAGAAAGAAAGAATGAATGAGAACGAACAAACAAGACAATAAGAAAGAAAGGACGATCGAGAAAGAATAAAAGAACAAATGAACAAGAAAGGAAAAAAAATGACCAGGTTTGTGGGCACTGCCGGAGATGAATCAAACAAAAATAGCTAGCAAGTGAAAAATCAAATATGTAGTAAAAATGTACATTTCACGCACGCACACACAAAGCAAAGAATGTTGGTCGACCACTTGGTTCTCTTAGTTAACTACAAGACCCTAAAATCAAACTTTAAAGGTCAGTCTAACCATCAGTTTGTGTTCAGGGGTGGACTGCGATATCGATGTGCCCAAGACTATCCAGATGGTGCGATCTCAGCGTTCAGGAATGGTACAGACTGAAGCACAGTATCGCTTCATCTACATGGCCGTACAGCATTATATTGAGACTCTGCAGCGCCGCATAGAGGAGGAGCAGG[T/C]GTGTACACTTACAGTGGGGGAGATAAGTATTGAACACATAACCATTTATCTCAGAAAACACATTTTTAAAGGCATCTAAAGGTGCTGTTGACTTGAAATTTTGACCAGATGTTGATAGCAACCAAATAAACTATAAAAGTAACTGTTTAGATTACAAATGAAGTTATGTGTAATAAAATAAAATGACACAGGGAAAAAGTATTGAACATATGAAGAACGTGAGGTGTAGAAAGCCAGTAAAAGCCCAGGCAGTAGCTGAAATCTCAGTAGTTCTTTAGCAACCCTCTGCCCTTCCTCAGTGTAAATGAATATCAGCTGCTTCAGTCCAACATCTACATTAGCAGGAGGATGAAGATGAAACCAGGGAAGACATTTCAACAAGACAATGATCCAAAACACAGCCAAATGCTTTCAGAGAAAAAAAATCAAGCTGTAGAATGGCCTAGCCAATCACCTGACTTAAACCCAGTAGAAAATACAAATTAAAGATCAGATTTGAT

Associated Phenotype:

Not determined