ZMP
ret1
Ensembl ID:
ZFIN ID:
Description:
proto-oncogene tyrosine-protein kinase receptor Ret [Source:RefSeq peptide;Acc:NP_858048]
Human Orthologue:
RET
Human Description:
ret proto-oncogene [Source:HGNC Symbol;Acc:9967]
Mouse Orthologue:
Ret
Mouse Description:
ret proto-oncogene Gene [Source:MGI Symbol;Acc:MGI:97902]
Alleles
There are 7 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa42210 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| hu2846 | Nonsense | Available for shipment | Available now |
| sa35492 | Essential Splice Site | Available for shipment | Available now |
| sa15240 | Nonsense | Available for shipment | Available now |
| sa22307 | Nonsense | Available for shipment | Available now |
| sa2684 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa42210
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000077627 | Nonsense | 59 | 1106 | 2 | 20 |
| ENSDART00000139237 | Nonsense | 41 | 1046 | 1 | 18 |
Genomic Location (Zv9):
Chromosome 13 (position 25827659)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 13 | 25473319 |
| GRCz11 | 13 | 25603769 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCGTTGCTTCAGGTCATTTCAATGCGGGAATTCCCTACAGAGAGGCCTTA[T/G]TTCTTCCTGTGCTCGCACAGAGACGCTTTTACATCATGGTTTCACATAGA
Long Flanking Sequence:
AACTTGTTATTAGACATTTACAGGATAAAATAGATATTAACAATCTACTCAAACCAATAAATCCTTTGTCAAGTCCTCTGCATTATTTAATCTTTAAAGTTGTTCTTGTCTATTTAATGTTCATCTGAGGTTCAGTTTTCTTGCAAACGTCCTGCGGAGTCAGATTAAATTTTTTTGACTCAAATGCTTTTGGTCTGAACTTGTATTGAACCCAGAATATCCATTTATTCCATTGTTAAAATGATGAAAGTGCTACGATTTCTTCATTGGTGATGGATGTAAAAAGTGTGTAAAGGACAGCCAAAATGTGACAATGTCTGGATCCGAAACTGAAATATTAAATCTCTGTGGTGTTATATTTGCTGTGTGTTTTGGACAGGTTCATTCGGGCTGTATTTTCCTCAAAGGCTTTACACAGAGAACATCTACGTGGGTCAGCAGCAGGGATCACCGTTGCTTCAGGTCATTTCAATGCGGGAATTCCCTACAGAGAGGCCTTA[T/G]TTCTTCCTGTGCTCGCACAGAGACGCTTTTACATCATGGTTTCACATAGATGAGGCGTCCGGAGTTCTTTATCTCAACAAAACCCTGGAGTGGAGCGACTTCAGTAGTTTACGTGAGTTCAACATATCCACTGAAAGAAATGATTCATTGGATTTACTAAATGTTTTTTAAGGTAAGTGGTTGCAAACAATTAATATGGGCTGAATTTAAAAAACAAACAAATTAAATTGAACATTACAAAATTTAATTTGCTCATTTAAAACCAGCCCATATACATAGTTTGCAATCACTTACCTTAAAAAAACATTTAGTAAAAGTATATATTTAGTTTATAGAAAGAACCATTGTAATTTTCTTCATTATTTTGCTTATATATTCTGGGTATTCTTGGATTTTATGGGTTTAAATTGTTCGTATCATTTTATTGTACTCATATATTTTATGTTATTTTAATACAATTTTAATTTACTTATAAAGTAAAATAATAAATAAATAAATCC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
hu2846
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000077627 | Nonsense | 229 | 1106 | 4 | 20 |
| ENSDART00000139237 | Nonsense | 211 | 1046 | 3 | 18 |
Genomic Location (Zv9):
Chromosome 13 (position 25824425)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 13 | 25470085 |
| GRCz11 | 13 | 25600535 |
KASP Assay ID:
554-0012.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCACAAGTGGACCGCGAGGAGAAGGAAGTGTATCATCTGGATATAGTCTG[T/A]ATGGTACGAACAGAAAGAAATCTGGAGGAGGTCTTCAGATCTTTACATGT
Long Flanking Sequence:
TTTAATGGTAGAAAATAGTTTCACATTGGGCTGTTTAGCAGAGCTCACCATGCAACAAACAAAATAAGTATTGTAAATTGATAAAAGAAGGCACATTATGCTGATTTGTTGTATATTTAATGATGTTAGATGGTTAGCTAAATGCATTTGATCAATTATAGTCAATAAATCTTTGCTAAATGTGTTTGTAAAAGCTGTTTTTGATACATTTTTGACATGGGTTTTTGTTGTATTTGCACAGATTTGACCAGCAGAGTTACTCAGTCTGTGATCATTTGAACACTTCAAAATCATTATATGAAGCAATTGGTCTAAGTCATTTAAAGATTTGGAAAACTTATTTTCTCCCGTCACTACTCTAAGATGGATTGTCTGTGCTTGTTTATATTTAATTCAGGATCTTCTGTACCGTTTGCGGTCGACGACTCCACTTCTGAACTAGTGGTCACAGCACAAGTGGACCGCGAGGAGAAGGAAGTGTATCATCTGGATATAGTCTG[T/A]ATGGTACGAACAGAAAGAAATCTGGAGGAGGTCTTCAGATCTTTACATGTGAACATCTATGATGAAGATGATAATTCTCCTTATGTCAACGGGACTGACACTGAAGACGTCTTAGTAGAGTTTGACCGCAGTGAGGTGTGTGCTATTTTGTGTGTGTGTGTGTGTGTAATCTTCTTAGCTTTTTTGATCTTGTATATTAATAAGCTTTTCTCTTTTGTAGGGTACTGTGTTTGGGACTCTGTTTGTATATGACAGAGACACAACACCAGTTTATCCCACAAACCAAGTTCAAAATAAACTGGTGGGGACCCTGATGACAAATGACTCCTGGATCAAAAATAATTTTGCTATTGAACACAAGTTTAGGGAAGAGAAAGCTATTTTTGGAAATGTCCGTGGGACTGTTCATGAATACAGTGAGTACAAAAACAGTTTTTTGCTTATTTTTAAACATAATTTTAGTGCTTTTAAAAATGTTTTTCCTCTTGGTGTTTATCTCA
Associated Phenotype:
This allele has been associated with this phenotype by genetic linkage analysis and may not be causal.
See FAQs for more info.
See FAQs for more info.
| Stage | Entity | Quality | Tag |
|---|---|---|---|
| Larval:Day 5 ZFS:0000037 |
ventral mandibular arch ZFA:0001273 |
quality PATO:0000001 |
abnormal PATO:0000460 |
Mutation Details
Allele Name:
sa35492
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000077627 | Essential Splice Site | 619 | 1106 | 10 | 20 |
| ENSDART00000139237 | Essential Splice Site | 601 | 1046 | 9 | 18 |
Genomic Location (Zv9):
Chromosome 13 (position 25817707)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 13 | 25463367 |
| GRCz11 | 13 | 25593817 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGTTACTGCTTTGAAGGAAAGTGCTTCTGTGAAAGAGATGAACCGGAGGG[T/C]GAGCTGCAGCTGATTGTTTTTTTCTCTGTAAAGATTGTATTTTTTATATT
Long Flanking Sequence:
CGACTCGAGGCCTGGGAGCCCCAACAGGGAGATGCCAGTGGAGACAAGGCCGAGATAAAGGTTACCCACAATCCCCTTGACTACTACAAGGACGTGCAAATCAAATACACTGCACTTTACTTTATTATTGTGTTTGCTGAAAAACTAATTCTGTGTTGTTTGCAGGAATATCAAAAAGATACTCCACCTGTTCCCCCAACCTCGGCACGTGCCCTGATGGTTACTGTGATGCCATTGAGAGCAAGAACATCTCCATCTGTCCTCAGGATTGCTCCAGTAAGACGTATTTGAGCACTTGTTTTGGTGCAGTGTTGTTTAGTTTGATCAGCATAATTGTGCAATGGTGCATTAAGGAAGTGAAATGTCTATATCTGTGTCTTTTTGTCAGGTGAGGCCATAATCGGCGGTTATGAAAGGGACCTGTATGGAATCAAAGCTGGACATGGGACCTGTTACTGCTTTGAAGGAAAGTGCTTCTGTGAAAGAGATGAACCGGAGGG[T/C]GAGCTGCAGCTGATTGTTTTTTTCTCTGTAAAGATTGTATTTTTTATATTATTTTCGGACTTTCGTAACTTCACAGAAGATAAATTAAGAAGTTCTCAAAGTTAACAGAATTGGGGATTATTTTATTATAGTTGCAAAACTTTTGTATCAGTTGTTTGTTTAGGTATTTATTTATTTTTTTATTTAAATAGACATGGACCTCACAATTACACTGGACAAGTGTTTTAGCATACTTGCTAACTCTCAACAACTATCCACAGGAGCCTTGACCTAAAATGAAACTAAAATAGATACATATAAACTATTATAAACATTAAAACACATTATAAACATATACATTTATAAATTTATAAATTATAAACACATCATTTTTTCCATAAAATTGCTATAAGGTAAAAGCATAGTCAGCATGATCAAACAAACTAATAGTATTTATTTATTATTTATTTATGTAAACACTGCTGTTTTATTTTTAACCTCTTTTTAAGAACACTACTAAA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa15240
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000077627 | Nonsense | 760 | 1106 | 13 | 20 |
| ENSDART00000139237 | Nonsense | 742 | 1046 | 12 | 18 |
Genomic Location (Zv9):
Chromosome 13 (position 25814990)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 13 | 25460650 |
| GRCz11 | 13 | 25591100 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AAATKACTYTAACCATTMATTTTTTCACCACAGAAAATGCRTCTCACAGC[G/T]AGCTTCGAGAYCTCCTSTCAGAGTTCACATTGCTYAAGCAGGTTAATCAC
Long Flanking Sequence:
TAGAGTCAACTCATTGTCATGTTCAAGAAACCAGTCTGAAGTAATTCGCGCTTTATGACATGACGTGTAATCCTGCTGGAAATAACCATCAGAAGATGGGTACAATGTGGTCATAAGGGGATTGACATGATCAGCAACAATTCTTAGGTAGGCTGTGGCATTGACACAATGATCAATTGGTACTAATGGGCCCAAAGTGTGCTAAGAAAATATCCCCCACACCATTTCACCACCTCCACTTGCCTGAATCATTGATACAAGGCAGGATGGATCCACACTTTCATGCCTAAATGCATCAAGTTTCTGCCATGTGATTGACTGAGTAGATATTTGCATTAATGAGCAATTGGACAGGTGTACCTAATAAAGTGGCCGGTTAGTGTATGTCATTTGCATATGTTGCCATCAGATTTCTGTGTGGGATGCATTTGATCAAATCACTTTAGTCTGAAATTACTCTAACCATTCATTTTTTCACCACAGAAAATGCATCTCACAGC[G/T]AGCTTCGAGACCTCCTCTCAGAGTTCACATTGCTTAAGCAGGTTAATCACCCTCATGTCATTAAAATGTATGGAGCTTGCAGCCAGGATGGTAAGATGTTATACACAAACACCTGTATGTTCATTTCATGCATTTGTTTCCACTTTGCTGTGTGTGCTTACTTATGTTAATGTGTTCAGGTCCATTATACTTAATTGTTGAATACGCCAAGTATGGTTCACTACGTAACTTCCTGAGAGAGAGCCGCAAAGTTGGGCCAAGCTATATGGGCAATGATGCCAACCGCAACTCCAGCTACTTGGAAAACCCAGACGAGAGAGCTCTGACCATGGGCGACCTGATCTCGTTCGCCTGGCAGATCTCTAGAGGAATGCAATACCTAGCTGAGATGAAGGTATGCCAGTGATTTGAGGAAAATATACAACACCGAATACCTGATGTTCTATTTTTAAAGAAAATTTATAAAGGGAAAATTTGTATTAAGCTTGTTCACAGAGACC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa22307
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000077627 | Nonsense | 800 | 1106 | 14 | 20 |
| ENSDART00000139237 | Nonsense | 782 | 1046 | 13 | 18 |
Genomic Location (Zv9):
Chromosome 13 (position 25814781)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 13 | 25460441 |
| GRCz11 | 13 | 25590891 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TACTTATGTTAATGTGTTCAGGTCCATTATACTTAATTGTTGAATACGCC[A/T]AGTATGGTTCACTACGTAACTTCCTGAGAGAGAGCCGCAAAGTTGGGCCA
Long Flanking Sequence:
ATATCCCCCACACCATTTCACCACCTCCACTTGCCTGAATCATTGATACAAGGCAGGATGGATCCACACTTTCATGCCTAAATGCATCAAGTTTCTGCCATGTGATTGACTGAGTAGATATTTGCATTAATGAGCAATTGGACAGGTGTACCTAATAAAGTGGCCGGTTAGTGTATGTCATTTGCATATGTTGCCATCAGATTTCTGTGTGGGATGCATTTGATCAAATCACTTTAGTCTGAAATTACTCTAACCATTCATTTTTTCACCACAGAAAATGCATCTCACAGCGAGCTTCGAGACCTCCTCTCAGAGTTCACATTGCTTAAGCAGGTTAATCACCCTCATGTCATTAAAATGTATGGAGCTTGCAGCCAGGATGGTAAGATGTTATACACAAACACCTGTATGTTCATTTCATGCATTTGTTTCCACTTTGCTGTGTGTGCTTACTTATGTTAATGTGTTCAGGTCCATTATACTTAATTGTTGAATACGCC[A/T]AGTATGGTTCACTACGTAACTTCCTGAGAGAGAGCCGCAAAGTTGGGCCAAGCTATATGGGCAATGATGCCAACCGCAACTCCAGCTACTTGGAAAACCCAGACGAGAGAGCTCTGACCATGGGCGACCTGATCTCGTTCGCCTGGCAGATCTCTAGAGGAATGCAATACCTAGCTGAGATGAAGGTATGCCAGTGATTTGAGGAAAATATACAACACCGAATACCTGATGTTCTATTTTTAAAGAAAATTTATAAAGGGAAAATTTGTATTAAGCTTGTTCACAGAGACCTGGCTGCAAGGAATGTGCTGGTGGCAGAAGGAAGGAAGATGAAAATATCAGACTTTGGTTTGTCTCGAGATGTCTATGAGGAAGATTCATACGTGAAGAGGAGCAAGGTGATCTATTTTGTTAAACTGCATTAAATTAGTCACACGCCCCCACCGATGTTTTAATGGGTCTAATTATTCCTTTAGTTTGTAATGTTGTTATTTGTACGG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa2684
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000077627 | Nonsense | 849 | 1106 | 14 | 20 |
| ENSDART00000139237 | Nonsense | 831 | 1046 | 13 | 18 |
Genomic Location (Zv9):
Chromosome 13 (position 25814634)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 13 | 25460294 |
| GRCz11 | 13 | 25590744 |
KASP Assay ID:
554-2592.1 (used for ordering genotyping assays)
KASP Sequence:
ACCCAGACGAGAGAGCTCTGACCATGGGCGACCTGATCTCGTTCGCCTGG[C/T]AGATCTCTAGAGGAATGCAATACCTAGCTGAGATGAAGGTATGCCAGTGA
Long Flanking Sequence:
GTACCTAATAAAGTGGCCGGTTAGTGTATGTCATTTGCATATGTTGCCATCAGATTTCTGTGTGGGATGCATTTGATCAAATCACTTTAGTCTGAAATTACTCTAACCATTCATTTTTTCACCACAGAAAATGCATCTCACAGCGAGCTTCGAGACCTCCTCTCAGAGTTCACATTGCTTAAGCAGGTTAATCACCCTCATGTCATTAAAATGTATGGAGCTTGCAGCCAGGATGGTAAGATGTTATACACAAACACCTGTATGTTCATTTCATGCATTTGTTTCCACTTTGCTGTGTGTGCTTACTTATGTTAATGTGTTCAGGTCCATTATACTTAATTGTTGAATACGCCAAGTATGGTTCACTACGTAACTTCCTGAGAGAGAGCCGCAAAGTTGGGCCAAGCTATATGGGCAATGATGCCAACCGCAACTCCAGCTACTTGGAAAACCCAGACGAGAGAGCTCTGACCATGGGCGACCTGATCTCGTTCGCCTGG[C/T]AGATCTCTAGAGGAATGCAATACCTAGCTGAGATGAAGGTATGCCAGTGATTTGAGGAAAATATACAACACCGAATACCTGATGTTCTATTTTTAAAGAAAATTTATAAAGGGAAAATTTGTATTAAGCTTGTTCACAGAGACCTGGCTGCAAGGAATGTGCTGGTGGCAGAAGGAAGGAAGATGAAAATATCAGACTTTGGTTTGTCTCGAGATGTCTATGAGGAAGATTCATACGTGAAGAGGAGCAAGGTGATCTATTTTGTTAAACTGCATTAAATTAGTCACACGCCCCCACCGATGTTTTAATGGGTCTAATTATTCCTTTAGTTTGTAATGTTGTTATTTGTACGGTGGCTGATAGAGGTCAAATGTTCTGCAAGAAAAGAAAGCACAATCCAATGAACAAAAAATTATGAACAAATTATGCAAATTATACAAATAATGAAAACCTCTTCATCAGTTTGACAACACACTTAAAATAAATTCTCACAACACATG
Associated Phenotype:
Normal
| Stage | Entity | Quality | Tag |
|---|---|---|---|
| Larval:Day 5 ZFS:0000037 |
whole organism ZFA:0001094 |
quality PATO:0000001 |
normal PATO:0000461 |