Busch Lab

ZMP

tp63

Ensembl ID:
ENSDARG00000044356
ZFIN ID:
ZDB-GENE-030819-1
Description:
tumor protein 63 isoform alpha 2 [Source:RefSeq peptide;Acc:NP_689454]
Human Orthologue:
TP63
Human Description:
tumor protein p63 [Source:HGNC Symbol;Acc:15979]
Mouse Orthologue:
Trp63
Mouse Description:
transformation related protein 63 Gene [Source:MGI Symbol;Acc:MGI:1330810]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
hu2525 Missense Available for shipment Available now
sa12599 Nonsense Available for shipment Available now
sa15970 Nonsense Available for shipment Available now
sa33878 Missense, Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
hu2525
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Missense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000065135 None None 434 None 11
ENSDART00000065137 None None 588 None 12
ENSDART00000123189 None None 440 None 10
ENSDART00000127965 Missense 48 632 4 15
ENSDART00000130799 None None 576 None 12
Genomic Location (Zv9):
Chromosome 6 (position 28572563)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 28868206
GRCz11 6 28858767
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCAATGCAGCCTATCGAGCTCAATTTCTCTGAGGGCTCTTCGGTCGGAT[C/T]AGCATCCAATACTATACAGATTAGCATGGACTGCATCACAATGCATGGGC
Long Flanking Sequence:
GGCATGCTCCCTGTGCAAGCAAGCGGTCTGTTTTGATAATATTAACAAAAGTTTGTCAAATGTCAGCCACTGTGTTGTGTAATATTATTGTCTTGAAAATAGTAACTTTTCATTTTCCATCAGGCTTAGTACACAGTGAAGCTACAGAAGAATTAAGCTTTAAATGCCAAAATAATTGGTGAAAATCTTTGCTTATTATTTGAGTGAGATGCTTGTAGTTTTATCTGATTTAATAATCTTAACTAAGCTAAGCTAAAAGTGCTCCTCACTGACCCCGAGGTTGTCTAAATGGATTCAAAAATGGTAAAACGAATTTCTTAACTCTAAGGGAAAAAAAAAAGTGTAGCGCTCCTGTAACTGTTGTATGTGTCAAAAAATTAAGGTTTATATAAAATAAGGTTTATATAAATATATAATATATAATTCACTCTGTTTTAGGTCTGCATTACATTCAATGCAGCCTATCGAGCTCAATTTCTCTGAGGGCTCTTCGGTCGGAT[C/T]AGCATCCAATACTATACAGATTAGCATGGACTGCATCACAATGCATGGGCCTGAGGAGCCCCTTACAGTAAGTACTTATTTTCATTAAACTGCTGCACGTTTGAAACTGCATCAAAATGTGATTAAATAGCACACTTTCTTCAGTGATAATGCAGTGACATGAAGATCTGAGGAGGTGCCAGTGGTCAGGACACATTTTCGAATTTCAAGATTTCAGACTATATAGAATTCTGGTTCTGATCTTCCTCAATTAATTTAGCCAAACATAGCTGATGGCTGCCCTTAAAATTTCCTCCAAATATTTATTAACCTTTAATAAGGTTAGGATATGTTCACAGAGGCAGTTCAGTTCTCTTGGTTCTATTGGTAAGACAGTTATACTGTCTTTTTTAATGCAAATTGATGGTATTTTTAATATTTGTGAACTTGTGAAGAGTTTTTGAAATAGTAGTAGGGCCAGACAGAATCTGTGGACATTTTTTGCTGTTTCTGCACAAGAT
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461

Mutation Details

Allele Name:
sa12599
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000065135 Nonsense 147 434 3 11
ENSDART00000065137 Nonsense 147 588 3 12
ENSDART00000123189 Nonsense 147 440 3 10
ENSDART00000127965 Nonsense 203 632 6 15
ENSDART00000130799 Nonsense 147 576 3 12
Genomic Location (Zv9):
Chromosome 6 (position 28611435)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 28907078
GRCz11 6 28897639
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GGGCCATGCCTGTCTATAAGAAAGCAGAGCATGTTACTGAGGTGGTCAAA[C/T]GMTGCCCGAACCAYGAGCTGAGCAGAGAGTTCAATGACGGTATGCCACTC
Long Flanking Sequence:
GCTATTGAAAAAAAGCTTAAAGGGGCTAATAATTTTAACCTTAAAAGGGTGTTTAAAAAGTTAAAACTGCTTTTATTTTAGTTGAAATAAAACAAATAAGACTTTCTCTAGAATAAAAAAATATTATCAGACATACTGTGAAAATTCCCTTGCTTTGTTAAACAACATTTGGGAAATATTTAAAAATGTATGTATGTATGTATGTTTGTTTGCATGTATATATGTACGTGTTTTTATATATATTTATATAACTTCTCCAGTTTTTTAATGTTTATTTATTGGATTGGGAAAAAAGAAAGAATATTAATATTATTTGCTATGTGTAACCATGCTCGTCTCTCTGTTTTCTTTAGTACTCCACAGAGTTGAAGAAGCTGTACTGTCAGATTGCCAAAACATGTCCTATTCAAATCAAGGTCCTAACCAACCCACCCCAGGGTGCAGTCATACGGGCCATGCCTGTCTATAAGAAAGCAGAGCATGTTACTGAGGTGGTCAAA[C/T]GATGCCCGAACCACGAGCTGAGCAGAGAGTTCAATGACGGTATGCCACTCTTTTGTAATTGGACTGTATAAATTTGGCTAAACATTTTAATGTTCCATATAATTTACTGATTTTGTGTTCAATAGGCCAAATAGCCCCACCCAGTCACCTTATTAGGGTTGAGGGGAACAGTCACGCTCAATACGTGGAGGATTCCATTACTGGGCGTCAAAGTGTGCTGGTGCCTTATGAGCCCCCTCAGGTGAACACACACATACACACACCTACAATTACAGAAGAACTGCAGTGAACCTGGCTGTTCCTACAAACCCTGCACACCTGAAAGCACTCCCAGCAGATGTTAAAGCATTAGTTCAGTTCAAAATGAAAGTCTTTTACTCACCCTCATGACGTTTTAAGTAAACTCTTGTACATATACGGAACACACATGAATGTATTTGTGATCTTATTTGAGAGATTAAAGTTAATACAGATCAAACCAAATTTTATTTTTAATGTAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa15970
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000065135 Nonsense 312 434 8 11
ENSDART00000065137 Nonsense 312 588 8 12
ENSDART00000123189 Nonsense 316 440 8 10
ENSDART00000127965 Nonsense 368 632 11 15
ENSDART00000130799 Nonsense 312 576 8 12
Genomic Location (Zv9):
Chromosome 6 (position 28615154)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 28910797
GRCz11 6 28901358
KASP Assay ID:
2259-7624.1 (used for ordering genotyping assays)
KASP Sequence:
TACCCCATCNNNNCTCTCTCTCTCWGTGCTTCAGATTAAAGGCCGTGAAATCTA[T/G]GAGATTTTGGTGAAAATCAAAGAGTCTTTGGAACTCATGCAGTTCCTCCC
Long Flanking Sequence:
GACGTATTCTTTTATGTTTTAAATCATTAAAAACAAATGAAATGTAAGCTCTAATATGTAAATCAGTTAGTATTTGGGGCTGCACTGTGATCCTTAAATAATCTTTTAATAGTTGTCAGATGAAATTAGTTTTATATGCCAGGCAATATTTTAGTTTGAAACACATTTAAACCGTGCTTGACAGAAATTGGTTCTGCTCAGAAAACAATACATAATTATGAATAGGATAAATAATGTTCAACAAAAGAATCTAAACTATATTACATGTGGTTGTGCTTAAAAGCACCTTTTTTATCTGACCCATGTATGTAGGCTTTTTCTCGAAAGTGGGAACGAATATTTGATAAAGAAAAGAAAAAGCATAATATTCAAAGATTATCTTCCAGACTTTCATGTTTTGAGTAGGCGTTGAAAATGAAGAGCATAATGTAAGAGTCTGACATCTAGACTTACCCCATCCTCTCTCTCTCTGTGCTTCAGATTAAAGGCCGTGAAATCTA[T/G]GAGATTTTGGTGAAAATCAAAGAGTCTTTGGAACTCATGCAGTTCCTCCCTCAGCAGACTATTGAGTCATACAGACAGCAGCAGCAGAACCTACTGCAGAAACAGTGAGTACCTTACATTTGCCGAAAAACAAATCCCCAATAATTATCAGCAATTTTCAATTGACAGATTATTTTCAAATAAATAATATGGGGAATATGTTTTCATAATGTGACTAGCAACAAGCAAGCTACACTAATCTAGCAAGGTCCACCCACAAACTGTTTTTTGTGTTTAACATGACACAAGCTTTCTTGCTTGCTTTTAACTCTTGTGGATTTGATTGTGATTGCGATTGCTCAATTGACTGGCCATAACTGACCTGACTTTGTCAGTCAGATAATTGTTTTTATTCTTTTAAAAATTAATTTCTGCCTCATCTGAGGGTCACTGTCACTTTAAAATGGCAGTTTAATTTTCTCACACTGTTGATACGGTATCAATATAAGCCAGGCTTATAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33878
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Missense, Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000065135 Missense 386 434 9 11
ENSDART00000065137 Nonsense 434 588 10 12
ENSDART00000123189 Nonsense 426 440 10 10
ENSDART00000127965 Nonsense 478 632 13 15
ENSDART00000130799 Nonsense 422 576 10 12
Genomic Location (Zv9):
Chromosome 6 (position 28624597)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 28920240
GRCz11 6 28910801
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTATGAACACAGACCTGAGCTCCTTGAGCCCCAACAACCCCCTCCAGTCA[C/T]AGTTACAAATGGTGCCTTCATCCCACTGCACACCTCCACCACCCTACCCG
Long Flanking Sequence:
CTTTACTTAATATTTCACTGATTATTGATGCTTGACCCCTACATTGCTTTTATTTTTATTTTTTCATGTTCAACGAGTGGTTTTGTGGTCCACGGTCACATATATTAATAGAAGTTATTTTCCGTTGCAATAATATTTTGAAGTATTACAGTTCAACCAAATGTAAAGCAAAAAGGAAAAAAATTAAAGCAAATTTTGAATGATGCAACACTTTATTTAACACTCAACGTTAATTCCTATTGGCTCATTGTAAAGCATTTGAAATGTCTTAAAGTGCAATGAATGAGCAAAGATTATTATGCTGTAAAAGTATTTCTCATTGTTGGTTCATAATGCATTGAACCACATTGTAAAGTGTTACCGTTTTATTTCCCCTTTTCTGAGGTTTATTACAGTCTCAACCCTTTCCCCTTCCTTCAGTGACCCCTCCTATGATGGGTGGCCCTGTTCCTATGAACACAGACCTGAGCTCCTTGAGCCCCAACAACCCCCTCCAGTCA[C/T]AGTTACAAATGGTGCCTTCATCCCACTGCACACCTCCACCACCCTACCCGATGGACAACAGCATTTCCAGGTACGCAGTAAGTCTCTCTGGAGTGGTATTTAAGTTGATGTTAAATGGCGTTATTGTAATCCTGGTTTAATCTGGAATCTCTTTCATTTGCAGTTTCCTGTTGAGGCTGGGCTGCTCGGCCTGTTTGGACTATTTCACAGCCCAAGGACTGACCAATATCTACCAGATTGAGAATTATAACTTAGAGGTGAGGAATTTGCCTTACTCTTACTGTCTTTTGCATCAGTTCAGATCTCAGGTCCAAAATTGCATAGAATTGATTACTATAGTATGCACTCACTTTTAAGCAGAGCTTAATTTGTAAATGAATAATTCCCGGAACAAAAGTAGGAAATAAAATTTACTGTGACTGACATCCACCAAACAATTTCAGTTTTTCCAGAACATGACGCCATTAAACAGTGATAGCGCAAAGGATCATCACATTTCT
Associated Phenotype:
Not determined